• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >The first autopsied case of diffuse Lewy body disease (DLBD): re-examination by recentimmunostaining methods
【24h】

The first autopsied case of diffuse Lewy body disease (DLBD): re-examination by recentimmunostaining methods

机译：首例尸体弥漫性路易体病（DLBD）的尸检病例：通过最新的免疫染色方法进行复查

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Materials from our first autopsied case of diffuse Lewy body disease (DLBD), that was originally reported in 1976, were re-examined using recent immunohistochemi-cal methods. Lewy pathology consisting of Lewy bodies and Lewy neurites appeared much more marked with alpha-synuclein immunostaining than had been detected with classical stainings. This case and our other similar cases prompted us to propose the terms "Lewy body disease" in 1980 and "diffuse Lewy body disease" in 1984. We also reported in 1990 that DLBD was classified into two forms: a pure form and a common form. Based on these studies the term "dementia with Lewy bodies (DLB)" was proposed in 1996. Since 1980, we have insisted that DLB, Parkinson disease (PD), and PD with dementia (PDD) should be understood within the spectrum of Lewy body disease. This insistence has been recently accepted by the International Workshop and the International Working Group on DLB and PDD in 2005 and in 2006, respectively.
机译：最初在1976年报道的第一例弥漫性路易体病（DLBD）尸检病例的材料已使用最新的免疫组化方法进行了重新检查。由路易体和路易神经突组成的路易病理学表现出的α-突触核蛋白免疫染色特征远比经典染色法所检测的明显。这个案例和其他类似案例促使我们在1980年提出“路易体病”和1984年提出“弥漫性路易体病”的术语。1990年我们还报道了DLBD分为两种形式：纯形式和普通形式。基于这些研究，1996年提出了“路易体痴呆症（DLB）”一词。自1980年以来，我们坚持认为应在路易思范围内理解DLB，帕金森氏病（PD）和帕金森氏病与痴呆症（PDD）。身体疾病。这种坚持最近已分别在2005年和2006年被国际讲习班和DLB和PDD国际工作组接受。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号