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首页> 外文期刊>Neuropathology: official journal of the Japanese Society of Neuropathology >A case of intracranial solitary fibrous tumor/hemangiopericytoma with dedifferentiated component
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A case of intracranial solitary fibrous tumor/hemangiopericytoma with dedifferentiated component

机译：一例颅内孤立性纤维瘤/血管内皮细胞瘤伴未分化成分

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摘要

We report the case of a 51-year-old Japanese man with an intracranial dedifferentiated solitary fibrous tumor/hemangiopericytoma (SFT/HPC) identified morphologically and immunohistochemically, comprised of a typical SFT/HPC with a high-grade pleomorphic component. NAB2-STAT6 fusion transcripts were detected by reverse transcriptase polymerase chain reaction in both the conventional and high-grade components. The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. Intracranial dedifferentiated SFT/HPC is a very rare but important differential diagnosis in intracranial pleomorphic tumors.
机译：我们报告的病例为一名51岁的日本男子，其颅内脱分化性孤立性纤维性肿瘤/血运细胞瘤（SFT / HPC）在形态和免疫组织化学上均已鉴定，其中包括典型的SFT / HPC和高度多形性成分。通过逆转录酶聚合酶链反应在常规和高级组件中检测到NAB2-STAT6融合转录本。两种成分中的肿瘤细胞均显示STAT6蛋白的核表达，表明这些检查的诊断价值。在颅内多形性肿瘤中，颅内去分化SFT / HPC是非常罕见但重要的鉴别诊断。

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