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首页> 外文期刊>Neuron >Hair-cell mechanotransduction and cochlear amplification.
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Hair-cell mechanotransduction and cochlear amplification.

机译：毛细胞机械转导和耳蜗放大。

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摘要

In the inner ear, sensory hair cells not only detect but also amplify the softest sounds, allowing us to hear over an extraordinarily wide intensity range. This amplification is frequency specific, giving rise to exquisite frequency discrimination. Hair cells detect sounds with their mechanotransduction apparatus, which is only now being dissected molecularly. Signal detection is not the only role of this molecular network; amplification of low-amplitude signals by hair bundles seems to be universal in hair cells. "Fast adaptation," the rapid closure of transduction channels following a mechanical stimulus, appears to be intimately involved in bundle-based amplification.
机译：在内耳，感觉毛细胞不仅可以检测到而且还能放大最柔和的声音，使我们能够在非常宽的强度范围内进行聆听。这种放大是特定于频率的，从而引起精细的频率区分。毛细胞通过其机械传导装置检测声音，该装置现在仅在分子上被解剖。信号检测不是该分子网络的唯一作用;发束对低振幅信号的放大似乎在毛细胞中很普遍。机械刺激后快速关闭转导通道的“快速适应”似乎与基于束的扩增密切相关。

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