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Prion infections of the brain.

机译:大脑的病毒感染。

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Prions are a rare cause of human disease but very important to recognize because of their potential for transmissibility and uniformly severe outcome. MR imaging plays an extremely important role in early diagnosis, especially with diffusion-weighted and fluid-attenuated inversion recovery images, which are the most sensitive for depicting prion-induced brain lesions. The lesions are characteristically shown as ribbons of cortical hyperintensity, or basal ganglia or thalamic hyperintensity. The cortical and deep lesions may appear alone or together, and although usually bilateral and symmetric, they may be asymmetric or purely unilateral. When these MRI findings are observed in an appropriate clinical context, the diagnosis of prion disease is very likely.
机译:ions病毒是人类疾病的罕见病因,但由于其具有传播性和严重后果的潜力,因此非常重要。 MR成像在早期诊断中起着极其重要的作用,尤其是对于弥散加权和液体衰减的倒置恢复图像,这对于描绘病毒引起的脑部病变最为敏感。病变特征性显示为皮质高信号带,基底神经节或丘脑高信号带。皮层和深部病变可能单独出现或一起出现,尽管通常是双侧的和对称的,但它们可能是不对称的或纯粹的单侧的。当在适当的临床环境中观察到这些MRI发现时,极有可能诊断出ion病毒病。

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