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首页> 外文期刊>Neurosurgical focus >Laser interstitial thermal therapy for subependymal giant cell astrocytoma: technical case report
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Laser interstitial thermal therapy for subependymal giant cell astrocytoma: technical case report

机译：激光间质热疗法治疗室管膜下巨细胞星形细胞瘤：技术案例报告

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摘要

Subependymal giant cell astrocytoma (SEGA) is a rare tumor occurring almost exclusively in patients with tuberous sclerosis complex. Although open resection remains the standard therapy, complication rates remain high. To minimize morbidity, less invasive approaches, such as endoscope-assisted resection, radiosurgery, and chemotherapy with mTOR pathway inhibitors, are also used to treat these lesions. Laser interstitial thermal therapy (LITT) is a relatively new modality that is increasingly used to treat a variety of intracranial lesions. In this report, the authors describe two pediatric cases of SEGA that were treated with LITT. In both patients the lesion responded well to this treatment modality, with tumor shrinkage observed on follow-up MRI. These cases highlight the potential of LITT to serve as a viable minimally invasive therapeutic approach to the management of SEGAs in the pediatric population.
机译：室管膜下巨细胞星形细胞瘤（SEGA）是一种罕见的肿瘤，几乎仅在结节性硬化症患者中发生。尽管开放式切除仍是标准疗法，但并发症发生率仍然很高。为了将发病率降至最低，还采用了侵入性较小的方法（例如内窥镜辅助切除术，放射外科手术和mTOR途径抑制剂的化学疗法）来治疗这些病变。激光间隙热疗（LITT）是一种相对较新的方式，越来越多地用于治疗各种颅内病变。在本报告中，作者描述了使用LITT治疗的2例SEGA儿科病例。在这两名患者中，病变对这种治疗方式均反应良好，在后续的MRI检查中观察到肿瘤缩小。这些病例凸显了LITT潜力，可作为一种可行的微创治疗方法来管理儿科人群的SEGA。

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