...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Nordic journal of psychiatry. >Prevalence of neuroleptic-induced movement disorders: an 8-year follow-up study in chronic schizophrenia inpatients
【24h】

Prevalence of neuroleptic-induced movement disorders: an 8-year follow-up study in chronic schizophrenia inpatients

机译：精神分裂症引起的运动障碍的患病率：一项针对慢性精神分裂症住院患者的8年随访研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Atypical antipsychotic drug use by schizophrenia patients in Estonia increased from 32% in 2004 to 61% in 2009.Aims: To assess the prevalence of neuroleptic-induced movement disorders in the Estonian institutionalized population of schizophrenia patients twice over a period of eight years, before and after introduction of atypical antipsychotic drugs using DSM-IV criteria.Methods: DSM-IV criteria and specific rating scales were used to evaluate the prevalence of neuroleptic-induced movement disorders among 72 patients who participated in the study in 2009 compared to 99 patients who participated in 2001.Results: Despite increased use of atypical antipsychotics in the study population (up to 30% from 20%), the proportion of movement disorder-free population remained the same over 8 years - 38.9% in 2001 versus 38.4% in 2009. There were significant intra-individual fluctuations. Use of a typical antipsychotic resulted in an almost seven times higher risk of tardive dyskinesia after 8 years. Doses of antipsychotic drugs had no effect on the severity of neuroleptic-induced movement disorders.Conclusions: Unfortunately, in 18% of patients the switch of medication from typical to atypical did not change the overall prevalence of neuroleptic-induced movement disorders in the group. The long-term benefit of atypical antipsychotics requires further research in patients who are treated with antipsychotics for years.
机译：背景：爱沙尼亚精神分裂症患者使用非典型抗精神病药的比例从2004年的32％增加到2009年的61％。目的：评估在八年的时间里两次在爱沙尼亚住院的精神分裂症患者中精神抑制药引起的运动障碍的患病率方法：采用DSM-IV标准和特定评分量表评估2009年参与研究的72例患者的精神镇痛剂引起的运动障碍的患病率，而99例中则为99例。结果：尽管参加研究的人群中使用非典型抗精神病药的比例有所增加（从20％上升至30％），但在过去的8年中，无运动障碍人群的比例保持不变-2001年为38.9％，而38.4％ 2009年。个人内部波动很大。使用典型的抗精神病药8年后，导致迟发性运动障碍的风险几乎增加了7倍。结论：不幸的是，不幸的是，在18％的患者中，将药物从典型改为非典型药物的使用并没有改变该组中精神抑制药诱发的运动障碍的总体患病率。非典型抗精神病药的长期益处需要对接受抗精神病药治疗多年的患者进行进一步研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号