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首页> 外文期刊>Nordic journal of psychiatry. >Assessing quality of life in patients with schizophrenia in an acute psychiatric setting: Reliability, validity and feasibility of the EQ-5D and the Q-LES-Q
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Assessing quality of life in patients with schizophrenia in an acute psychiatric setting: Reliability, validity and feasibility of the EQ-5D and the Q-LES-Q

机译：在急性精神病患者中评估精神分裂症患者的生活质量：EQ-5D和Q-LES-Q的可靠性，有效性和可行性

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Background: Quality of life (QoL) is considered an important outcome of treatment in psychiatry. Two QoL instruments, the EuroQoL-5D (EQ-5D) and the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q), have been increasingly used among patients with schizophrenia. Aims: The aim of this study was to investigate the reliability, validity and feasibility of the EQ-5D and the Q-LES-Q among patients with schizophrenia and related disorders (n = 311) in the most acute stage of their illness. Methods: The study was carried out in nine acute psychiatric wards of two psychiatric hospitals in Finland. The instruments' internal consistency, construct validity and missing values were evaluated. Results: Our findings show high internal consistency for the Q-LES-Q (Cronbach's alpha 0,89). For the EQ-5D, the Cronbach's alpha value was minimally acceptable (0.63) taking in to consideration the low number of items. Lower overall functioning indicated poorer QoL measured by the EQ-5D (U = 3098, P < 0.001) or the Q-LES-Q (U = 3357, P < 0.001). Missing values in the EQ-5D ranged from 6% to 7% and in the Q-LES-Q from 6% to 31%. Conclusion: Our results suggest that both QoL scales are reasonably reliable, valid and feasible in this patient group. The decision regarding which instrument to use would depend on clinical or research questions. When more detailed information for patients' satisfaction with QoL is needed then the Q-LES-Q would be a better choice, whereas if the primary interest is to briefly assess patients' QoL problems related to health status the EQ-5D would be a better choice.
机译：背景：生活质量（QoL）被认为是精神病学治疗的重要成果。精神分裂症患者越来越多地使用两种QoL仪器，即EuroQoL-5D（EQ-5D）和生活质量和满意度调查表（Q-LES-Q）。目的：本研究的目的是研究在疾病最急性期的精神分裂症及相关疾病（n = 311）患者中EQ-5D和Q-LES-Q的可靠性，有效性和可行性。方法：该研究在芬兰两家精神病医院的九个急性精神病房进行。评估了仪器的内部一致性，结构效度和缺失值。结果：我们的发现表明Q-LES-Q（克伦巴赫的alpha为0.89）具有很高的内部一致性。对于EQ-5D，考虑到少量物品，Cronbach的alpha值是最小可接受的（0.63）。总体功能较低表示通过EQ-5D（U = 3098，P <0.001）或Q-LES-Q（U = 3357，P <0.001）测量的QoL较差。 EQ-5D的缺失值介于6％至7％之间，而Q-LES-Q的缺失值介于6％至31％之间。结论：我们的结果表明，该患者组的两个QoL量表均相当可靠，有效且可行。关于使用哪种仪器的决定取决于临床或研究问题。如果需要更详细的信息来使患者对QoL满意，那么Q-LES-Q将是一个更好的选择，而如果主要目的是简要评估患者与健康状况有关的QoL问题，则EQ-5D会更好。选择。

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