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首页> 外文期刊>Nordic journal of psychiatry. >Is there a difference in subjective experience of cognitive function in patients with unipolar disorder versus bipolar disorder?
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Is there a difference in subjective experience of cognitive function in patients with unipolar disorder versus bipolar disorder?

机译：单相情感障碍与双相情感障碍患者的认知功能主观体验是否有所不同？

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Background: Cognitive dysfunction in unipolar disorder (UD) and bipolar disorder (BD) may persist into remission and affect psychosocial function. Executive and memory deficits during remission may be more pronounced in BD than UD. However, patients' subjective experience of cognitive difficulties is poorly understood, and it is unclear whether BD and UD patients experience different cognitive difficulties. Aims: To investigate whether there are differences in the quality and magnitude of subjective cognitive difficulties between UD and BD, and which factors influence the subjective cognitive difficulties in these patients. Methods: Patients with BD (n 54) or UD (n 45) were referred to the outpatient mood disorder clinic at Department of Psychiatry, Copenhagen University Hospital, following hospital discharge. Affective symptoms and patients' experience of cognitive symptoms were assessed at their initial consultation at the clinic. Results: Patients experienced mild to moderate cognitive impairment despite being in partial or full remission, but there were no differences in subjective difficulties between BD and UD. Subjective cognitive dysfunction was predicted by depression severity, anxiety and mania symptoms rather than by diagnosis, age, gender or alcohol misuse. Conclusion: The absence of difference in subjective cognitive difficulties between UD and BD contrasts with evidence of greater objective dysfunction in BD. This highlights a potential discord between subjective and objective measures of cognitive function. Subjective cognitive function was predicted by affective symptoms, perhaps suggesting that this reflects mood symptoms rather than objective deficits. This points to a clinical need for objective assessment of cognitive function in these patient groups.
机译：背景：单相情感障碍（UD）和双相情感障碍（BD）的认知功能障碍可能会持续缓解并影响社会心理功能。缓解期间执行力和记忆力障碍在BD方面可能比UD更明显。然而，患者对认知困难的主观经验了解甚少，尚不清楚BD和UD患者是否经历不同的认知困难。目的：探讨UD和BD之间主观认知障碍的质量和程度是否存在差异，以及哪些因素影响这些患者的主观认知障碍。方法：出院后，将BD（54例）或UD（45例）的患者转至哥本哈根大学医院精神病学部门的门诊情绪障碍诊所。情感症状和患者的认知症状经验是在诊所初诊时进行评估的。结果：尽管部分或全部缓解，患者仍出现轻度至中度认知障碍，但BD和UD之间的主观困难无差异。主观认知功能障碍是通过抑郁症的严重程度，焦虑和躁狂症状来预测的，而不是通过诊断，年龄，性别或酗酒来预测的。结论：UD和BD之间主观认知障碍的差异没有差异，这与BD客观功能障碍更大的证据形成了鲜明对比。这突出了认知功能的主观和客观度量之间的潜在矛盾。主观认知功能是由情感症状预测的，也许表明这反映了情绪症状而不是客观缺陷。这表明对这些患者群体的认知功能进行客观评估的临床需求。

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