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首页> 外文期刊>Nutrition & Food Science >Hypocholesterolemic effect of diet supplemented with Indian bean (Dolichos lablab L. var. lignosus) seeds
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Hypocholesterolemic effect of diet supplemented with Indian bean (Dolichos lablab L. var. lignosus) seeds

机译：日粮补充印度豆（Dolichos lablab L. var。lignosus）种子的降胆固醇作用

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Legume seeds provide one of the most concentrated sources of nutrients rich in fibre and high-quality protein in the diet. This study investigated the hypocholesterolaemic effect of germinated Indian bean (Dolichos lablab var. lignosus; lablab beans) by feeding albino rats with a hypercholesterolaemic diet. Male albino rats of Wistar strain were divided into 5 groups (each group consisting of 10 rats) according to randomized block design, housed in individual cages and fed with 1 of the 5 diets over an 8-wk period. At the end of 8 wk, the body wt. were recorded and the rats put down. Samples of blood and liver were collected and used for analysis of liver and plasma cholesterol. It was found that supplementation of the diet with dried powder of soaked bean almost brought the plasma cholesterol to 72.5 +or- 0.75 from 178 +or- 1.85 compared with that of the control (61.5 +or- 0.70), although the liver cholesterol was still 3x higher compared with the control. The 24 h germinated Indian bean cotyledons could effectively counteract the effects of added cholesterol on liver and plasma by their high fibre content coupled with enormous increase in ascorbic acid levels. Results suggest germination to be a simple biochemical tool to effectively lower the cholesterol levels in liver and plasma by virtue of its higher contents of ascorbic acid and dietary fibre in ischaemic heart disease patients.
机译：豆类种子是饮食中最丰富的营养物质来源之一，富含纤维和优质蛋白质。这项研究通过给白化病大鼠饲喂高胆固醇血症饮食，研究了发芽的印度豆（Dolichos lablab var。lignosus; Lablab豆）的降胆固醇作用。根据随机区组设计，将Wistar品系的雄性白化病大鼠分为5组（每组由10只大鼠组成），圈养在单独的笼子中，并在8周内喂食5种饮食中的一种。在8周结束时，身体重量记录下来并放下大鼠。收集血液和肝脏样本，并用于分析肝脏和血浆胆固醇。研究发现，在饮食中添加豆干粉可以使血浆中的胆固醇从对照组的178 +或-1.85几乎增加到72.5 +或0.75，而对照组的胆固醇是61.5 +或-0.70。仍然比对照组高3倍。发芽的24小时印度豆子叶可通过其高纤维含量以及抗坏血酸水平的大幅增加来有效抵消胆固醇对肝脏和血浆的影响。结果表明，由于缺血性心脏病患者中较高的抗坏血酸和膳食纤维含量，发芽是有效降低肝脏和血浆中胆固醇水平的简单生化工具。

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