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Meta-analysis of quality-of-life outcomes from physical activity interventions.

机译:身体活动干预对生活质量结果的荟萃分析。

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BACKGROUND: Interventions to increase physical activity among adults with chronic illness are intended to improve quality of life and reduce disease complications or slow disease progression. OBJECTIVE: The aim of this study was to integrate quality-of-life outcomes from primary research studies testing interventions to increase physical activity among adults with chronic illness. METHODS: Extensive literature searching strategies were used to locate published and unpublished primary research testing physical activity interventions. Results were coded for studies that had at least 5 participants with chronic illness. Fixed- and random-effects meta-analytic procedures included moderator analyses. RESULTS: Eighty-five samples from 66 reports with 7,291 subjects were synthesized. The mean quality-of-life effect size for two-group comparisons (treatment vs. control) was.11 (higher mean quality-of-life scores for treatment subjects than for control subjects). The treatment group pre-post comparison effect size was.27 for quality of life. Heterogeneity was modest in two-group comparisons. Most design and sample attributes were unrelated to intervention effects on quality of life. Studies that exclusively used supervised center-based exercise reported larger quality-of-life improvements than did studies that included any educational/motivational content. Effect sizes were larger among unpublished and unfunded studies. The effect size for physical activity did not predict the quality-of-life effect size. DISCUSSION: Subjects experience improved quality of life from exposure to interventions designed to increase physical activity, despite considerable heterogeneity in the magnitude of the effect. Future primary research should include quality-of-life outcomes so that patterns of relationships among variables can be explored further.
机译:背景:为增加患有慢性疾病的成年人的体育活动而进行的干预旨在改善生活质量并减少疾病并发症或减慢疾病进展。目的:本研究的目的是整合来自主要研究的生活质量结果,这些研究通过测试干预措施来增加患有慢性疾病的成年人的身体活动。方法:广泛的文献检索策略用于定位已发表和未发表的研究体育锻炼干预措施的主要研究。至少有5名慢性病参与者的研究对结果进行了编码。固定效应和随机效应的荟萃分析程序包括主持人分析。结果:来自66个报告的85个样本中有7,291名受试者被合成。两组比较(治疗组与对照组)的平均生活质量影响量为11(治疗组受试者的平均生活质量评分高于对照组)。治疗组的生活质量前后比较效果大小为27。在两组比较中,异质性是中等的。大多数设计和样本属性与干预对生活质量的影响无关。专门使用受监督的基于中心的锻炼的研究表明,与包括任何教育/动机内容的研究相比,生活质量的改善更大。在未发表和未资助的研究中,效应量更大。体育活动的效果大小不能预测生活质量的效果大小。讨论:尽管影响程度存在很大的异质性,但从接触到旨在增加身体活动的干预措施,受试者的生活质量得到改善。未来的主要研究应包括生活质量的结果,以便可以进一步探讨变量之间的关系模式。

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