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Effect of different calcium and phosphorus content in Mexican diets on rat femur bone growth and composition.

机译:墨西哥饮食中不同钙和磷含量对大鼠股骨生长和组成的影响。

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摘要

Mexican diets are high in phosphorus (P) with Ca/P ratios higher than recommended for optimum bone development. Beans and tortillas are the principal energy sources in the typical Mexican diet and these items are also the contributors of calcium (Ca) and P. In the typical Mexican diet (vegetable diet of this study), beans contribute substantial quantities of Ca (129 mg/d) and P (266 mg/d) and 274 mg Ca/d and 200 mg P/d for corn tortillas. When milk is included (mixed diet), milk provides, 447 mg Ca/d and 350 mg P/d. The objective of this study was to investigate the effect of different Ca and P content typically found in Mexican diets on the growth and composition of rat femurs. Weanling Sprague-Dawley rats were fed diets with different Ca and P content for 30 days, their femurs were extracted, weighed and the Ca and P content analyzed. Dietary Ca affects bone mass and Ca bone deposition (r=0.96;P<0.05) to a much greater extent than dietary P (r=0.71;P<0.05). Even though the P was higher than Cain the diets, the femurs had equal molar ratios of Ca and P. Ca and P content in the femur of rats fed both test diets increased but to a much lesser extent than when the animals were fed control diets. The animals fed the negative control diet or a dietdeficient in Ca and P, showed a significant loss of both Ca and P in the bone when compared to the initial values (P<0.05). On diets high in Ca, final size was larger and bone weights were larger. The rats fed the test diets had significantly (P<0.05) smaller femurs. The femur weight of the rats fed the vegetable diet did not differ in weight from those animals fed a diet deficient in Ca and P. Populations like Mexicans, who depend on beans and tortillas as their primary source of energy, as well as sources of Ca, in the diet, need to find ways to improve dietary Ca intake. Maintaining adequate Ca intake appears to be more important than Ca:P molar ratios.
机译:墨西哥饮食中的磷(P)含量很高,Ca / P比值高于建议的最佳骨骼发育建议值。豆类和玉米饼是典型的墨西哥饮食中的主要能源,这些物品也是钙和磷的贡献者。在典型的墨西哥饮食(本研究的蔬菜饮食)中,豆类贡献了大量的钙(129毫克)。 / d)和玉米饼的P(266 mg / d)和274 mg Ca / d和200 mg P / d。当包含牛奶(混合饮食)时,牛奶提供447 mg Ca / d和350 mg P / d。这项研究的目的是调查墨西哥饮食中常见的不同钙和磷含量对大鼠股骨生长和组成的影响。对断奶的Sprague-Dawley大鼠饲喂不同钙和磷含量的饲料30天,提取股骨,称重并分析钙和磷含量。饮食中的钙比饮食中的P(r = 0.71; P <0.05)对骨骼质量和钙沉积的影响更大(r = 0.96; P <0.05)。即使膳食中的P高于该钙,股骨中的Ca和P摩尔比也相等。两种试验饮食喂养的大鼠股骨中Ca和P的含量均增加,但比对照饮食喂养的动物低得多。与初始值相比,饲喂阴性对照饮食或缺乏钙和磷的饮食的动物的骨骼中钙和磷均明显减少(P <0.05)。在高钙饮食中,最终尺寸更大,骨骼重量更大。喂养测试饮食的大鼠股骨明显较小(P <0.05)。饲喂植物性饮食的大鼠的股骨重量与饲喂缺乏钙和磷的动物的体重没有差异。像墨西哥人这样的人口,他们依赖豆类和玉米饼作为其主要能量来源以及钙的来源在饮食上,需要寻找途径来提高饮食中钙的摄入量。保持充足的钙摄入似乎比Ca:P摩尔比更重要。

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