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首页> 外文期刊>Cell motility and the cytoskeleton >Effects of chemoattractant pteridines upon speed of D. discoideum vegetative amoebae.
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Effects of chemoattractant pteridines upon speed of D. discoideum vegetative amoebae.

机译：趋化性蝶啶对D. discoideum营养性变形虫速度的影响。

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Movements of D. discoideum vegetative amoebae responding to pteridine chemoattractants, folate acid and pterin, were recorded. A vector analysis of these images was performed to partition the speed and orientation components of these motility patterns. This study demonstrates that in addition to orientation (chemotaxis), stimulated speed (chemokinesis) is an important component of the directed migration of these amoebae. Furthermore, the primary difference in their response to folate versus pterin is in speed rather than orientation. The data support a model of directed migration of these cells in which there are (1) separate signal translation pathways consequent from folate versus pterin reception and (2) specific pathways leading to increase in orientation versus speed.
机译：记录了D. discoideum营养性变形虫对蝶啶趋化因子，叶酸和蝶呤的反应。对这些图像进行矢量分析，以划分这些运动模式的速度和方向分量。这项研究表明，除了定向（趋化性）外，刺激速度（趋化性）是这些变形虫定向迁移的重要组成部分。此外，它们对叶酸和蝶呤的反应的主要区别在于速度而不是方向。数据支持了这些细胞的定向迁移模型，其中存在（1）叶酸和蝶呤接收所导致的独立信号翻译途径，以及（2）导致方向与速度增加的特定途径。

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