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Leukocyte reactivity as an objective means of quantifying mental loading during ergonomic evaluation.

机译:白细胞反应性是在人体工程学评估过程中量化精神负荷的客观手段。

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摘要

Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56years) provided capillary blood samples before and after completing three basic tasks using, in turn, two automotive touch screen interfaces (Interface 1-antecedent version, Interface 2-improved version). Using a chemiluminescent technique termed leukocyte coping capacity (LCC), the ability of leukocytes to produce reactive oxygen species in vitro was assessed. Significant differences in leukocyte activity were shown between treatment groups, where the greatest post-test decrease occurred after using Interface 1. Phase 2: a randomly selected sub-group (n=4) underwent weekly repeat testing using both interfaces. Significant differences in post-test leukocyte reactivity were exhibited between test weeks for each interface-the magnitude of response decreasing with successive exposure.
机译:心理压力会引起心血管和神经内分泌系统的快速变化,这种反应在反复接触后会变得习惯。这项由两个阶段组成的研究表明,免疫系统遵循相似的趋势。阶段1:15位健康受试者(年龄在26至56岁之间)在完成三项基本任务之前和之后分别使用两个汽车触摸屏界面(接口1以前版本,接口2改进版本)提供了毛细血管血样。使用称为白细胞应对能力(LCC)的化学发光技术,评估了白细胞在体外产生活性氧的能力。在治疗组之间显示了白细胞活性的显着差异,其中在使用界面1后出现最大的测试后下降。阶段2:随机选择的亚组(n = 4)使用这两个界面每周进行重复测试。对于每个界面,在测试周之间显示出测试后白细胞反应性的显着差异-响应程度随连续暴露而降低。

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