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首页> 外文期刊>Cell cycle >Finding and keeping your partner during meiosis.
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Finding and keeping your partner during meiosis.

机译：在减数分裂期间寻找并保持伴侣。

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摘要

HIM-3 is a meiosis-specific protein that localizes to the cores of chromosomes from the earliest stages of prophase I until the metaphase to anaphase I transition in Caenorhabditis elegans. him-3 mutations disrupt homolog alignment, synapsis, and recombination and we propose that the association of HIM-3 with chromosome axes is a critical event in meiotic chromosome morphogenesis that is required for the proper coordination of these processes. The presence of HIM-3-like proteins in other eukaryotes, some of which are known to be required for synapsis and recombination, suggests the existence of a conserved class of axis-associated proteins that function at the junction of essential meiotic processes.
机译：HIM-3是一种减数分裂特异性蛋白，从秀丽隐杆线虫的前期I的最早阶段到中期I过渡到后期I过渡，定位在染色体的核心。 him-3突变破坏同源物比对，突触和重组，我们认为HIM-3与染色体轴的结合是减数分裂染色体形态发生中的关键事件，而这些过程是适当协调这些过程所必需的。其他真核生物中存在HIM-3-like蛋白，其中一些已知是突触和重组所必需的，这表明存在保守的一类轴相关蛋白，该蛋白在基本减数分裂过程的交界处起作用。

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