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Digital chest radiography: effect of temporal subtraction images on detection accuracy.

机译:数字胸部放射线照相:时间减影对检测精度的影响。

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PURPOSE: To improve early detection of disease in chest radiographs, the authors developed a digital processing technique that geometrically warps and subtracts a previous radiograph from a current radiograph to produce a temporal subtraction image. An observer test was performed to evaluate the effects of the temporal subtraction image technique on detection of interval change. MATERIALS AND METHODS: Fifty pairs of chest radiographs, including a baseline examination and a subsequent radiograph, were selected (25 cases in which potentially important new abnormalities had developed, and 25 in which there was no interval change). The baseline examination was chosen from multiple prior radiographs to minimize initial misregistration. By means of receiver operating characteristic (ROC) analysis, the ability of 11 observers to detect pathologic change when viewing the paired digitized baseline and subsequent radiographs was compared with their ability when viewing the same paired radiographs together with temporal subtraction images. Positive cases demonstrated focal new abnormalities that were greater than 1 cm in diameter. RESULTS: The mean area (Az) under the ROC curves increased from 0.89 without to 0.98 with the temporal subtraction images. When the paired digitized previous and current chest radiographs were viewed in conjunction with the temporal subtraction images, a significant improvement in detection of new abnormalities was achieved (P = .00004), whereas the mean interpretation time was reduced by 19.3% (from 52 to 42 seconds, including the time to record the score and to move to the next case) (P = .0019). CONCLUSION: The temporal subtraction technique can significantly improve sensitivity and specificity for detection of interval change in chest radiographs.
机译:目的:为了改善胸部X光片中疾病的早期发现,作者开发了一种数字处理技术,该技术可以几何变形并从当前X光片中减去先前的X光片以产生时间减影图像。进行了观察者测试,以评估时间减影技术对间隔变化检测的影响。材料与方法:选择50对胸部X光片,包括基线检查和随后的X光片(25例发生了潜在的重要新异常,而25例没有间隔改变)。从多个先前的X射线照片中选择了基线检查,以最大程度地减少初始配准不良。通过接收器工作特性(ROC)分析,将11位观察者在查看配对的数字化基线和后续X线照片时检测病理变化的能力与他们在查看相同的配对X射线照片和时间相减图像时的能力进行了比较。阳性病例表现出局灶性新异常,直径大于1 cm。结果:在时间相减图像下,ROC曲线下的平均面积(Az)从不存在的0.89增加到0.98。当与时间减影图像一起查看成对的数字化的先前和当前的胸部X线照片时,在检测新异常方面获得了显着改善(P = .00004),而平均解释时间减少了19.3%(从52 42秒,包括记录乐谱和移至下一个情况的时间)(P = 0.0019)。结论:颞叶减影技术可以显着提高检测胸部X光片间隔变化的敏感性和特异性。

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