A Novel Subcellular Collagen Organization Process Visualized by Total Internal Reflection Fluorescence Microscopy

Erik F. Young; Eugene E. Marcantonio

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A Novel Subcellular Collagen Organization Process Visualized by Total Internal Reflection Fluorescence Microscopy

机译：全内反射荧光显微镜可视化的新型亚细胞胶原组织过程

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The 1 1 and 2 1 integrins belong to a family of cell-surface molecules involved in structural contacts and signal-transduction events across the cell membrane. Employing two-dimensional substrates coated with fluorescently labeled type I collagen, we have discovered a novel subcellular matrix remodeling event that is particular to cells that express the fibrillar collagen receptor 2 1. Cells expressing 1 1 also perform this collagen organization process, but less proficiently. This work will provide a basis for subsequent studies of cell-mediated collagen fibril assembly.

机译：1 1和2 1整合素属于细胞表面分子家族，参与细胞膜的结构接触和信号转导事件。利用涂覆有荧光标记的I型胶原的二维基质，我们发现了一种新的亚细胞基质重塑事件，该事件特定于表达原纤维胶原受体2 1的细胞。表达1 1的细胞也执行此胶原组织过程，但效率较低。这项工作将为后续研究细胞介导的胶原原纤维组装提供基础。

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《Cell communication & adhesion》 |2007年第5期|共12页
作者
Erik F. Young; Eugene E. Marcantonio;
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正文语种 eng
中图分类细胞生物学;
关键词
collagen; integrin; matrix; remodeling;

机译：胶原;整合素;基质;重塑;

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1. A Novel Subcellular Collagen Organization Process Visualized by Total Internal Reflection Fluorescence Microscopy [J] . Erik F. Young, Eugene E. Marcantonio Cell communication & adhesion . 2007,第5期

机译：全内反射荧光显微镜可视化的新型亚细胞胶原组织过程
2. Lateral organization of a membrane protein in a supported binary lipid domain: Direct observation of the organization of bacterial light-harvesting complex 2 by total internal reflection fluorescence microscopy [J] . Dewa T, Sugiura R, Suemori Y, Langmuir: The ACS Journal of Surfaces and Colloids . 2006,第12期

机译：在支持的二元脂质结构域中膜蛋白的横向组织：通过全内反射荧光显微镜直接观察细菌捕光复合物2的组织
3. Subcellular and single-molecule imaging of plant fluorescent proteins using total internal reflection fluorescence microscopy (TIRFM). [J] . Vizcay-Barrena G., Webb S. E. D., Martin-Fernandez M. L., Journal of Experimental Botany . 2011,第15期

机译：使用全内反射荧光显微镜（TIRFM）对植物荧光蛋白进行亚细胞和单分子成像。
4. NANOSCALE CONTACT LINE VISUALIZATION BASED ON TOTAL INTERNAL REFLECTION FLUORESCENCE MICROSCOPY [C] . M. J. Z. Franken, C. Poelma, J. Westerweel International Symposium on Flow Visualization . 2010

机译：基于全内反射荧光显微镜的纳米级接触线可视化
5. Bayesian Multi-Target Tracking: Application to Total Internal Reflection Fluorescence Microscopy [D] . Rezatofighi, Seyed Hamid 2015

机译：贝叶斯多目标跟踪：在全内反射荧光显微镜中的应用
6. Visualization of Cortex Organization and Dynamics in Microorganisms using Total Internal Reflection Fluorescence Microscopy [O] . Felix Spira, Julia Dominguez-Escobar, Nikola Müller, 2012

机译：使用全内反射荧光显微镜观察皮层组织和微生物动力学
7. Visualization of Cortex Organization and Dynamics in Microorganisms, using Total Internal Reflection Fluorescence Microscopy [O] . Spira, F., Dominguez-Escobar, J., Mueller, N., 2012

机译：使用全内反射荧光显微镜观察微生物中的皮质组织和动力学

A Novel Subcellular Collagen Organization Process Visualized by Total Internal Reflection Fluorescence Microscopy

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