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首页> 外文期刊>Research journal of pharmacy and technology >Phytochemical composition, antioxidant, antimicrobial and cytotoxic potential of methanolic extracts of Adhatoda vasica (Acanthaceae)
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Phytochemical composition, antioxidant, antimicrobial and cytotoxic potential of methanolic extracts of Adhatoda vasica (Acanthaceae)

机译：豆科植物甲醇提取物的植物化学组成，抗氧化剂，抗菌和细胞毒性潜力

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摘要

The aim of this study was to evaluate Adhatoda vasica leaves for its phytochemical composition and antioxidant activity. Antioxidant activity of methanol extract of A. vasica was estimated by total antioxidant activity, 2,2 diphenyl-1-picrylhydrazyl radical scavenging activity, reducing power potential and iron chelating activity. Antimicrobial activity was performed by agar well diffusion method. Estimation of total phenolic content was measured by Folin-Ciocalteu reagent method and estimation of total flavonoid content was performed by aluminum chloride method. Leaves of A. vasica were found to possess saponins, oils and fats, phytosterol, phenolic compounds, tannins, carbohydrate, alkaloids, flavanoids and proteins. Extract showed high antioxidant activity in various antioxidant experiments. The extract of A. vasica showed presence of high levels of polyphenolic compounds (phenolic compounds and flavonoids), which could be the possible reason behind the antioxidant activity of the plant. In addition extract demonstrated moderat antimicrobial and cytotoxic activity (brine shrimp lethality).
机译：这项研究的目的是评估Adhatoda vasica叶片的植物化学组成和抗氧化活性。通过总抗氧化剂活性，2,2二苯基-1-吡啶并肼基自由基清除活性，降低电势和铁螯合活性来评估曲霉甲醇提取物的抗氧化活性。通过琼脂井扩散法进行抗菌活性。用Folin-Ciocalteu试剂法测定总酚含量，用氯化铝法测定总黄酮含量。发现A. vasica的叶子含有皂甙，油脂，植物甾醇，酚类化合物，单宁，碳水化合物，生物碱，类黄酮和蛋白质。提取物在各种抗氧化剂实验中显示出高抗氧化剂活性。 vas。vasica的提取物显示出高水平的多酚化合物（酚化合物和类黄酮）的存在，这可能是植物抗氧化活性落后的可能原因。此外，提取物还显示出适度的抗微生物和细胞毒活性（盐水虾致死性）。

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