...
首页> 外文期刊>Cell cycle >The role of BAFF-R dysregulation in B-lymphoid lineage malignancies.
【24h】

The role of BAFF-R dysregulation in B-lymphoid lineage malignancies.

机译:BAFF-R失调在B淋巴谱系恶性肿瘤中的作用。

获取原文
获取原文并翻译 | 示例
           

摘要

Emerging evidence implicates that the TNF superfamily member B lymphocyte stimulator (BLyS), also known as (B-cell activating factor) BAFF, as well as its receptors, particularly BAFF-R, as critical factors for the growth and survival of both normal and malignant B cells. Although the signaling pathways mediated through BAFF-R have been extensively studied recently, the transcriptional regulation of BAFF-R has not been elucidated, especially in lymphomas and leukemias.
机译:新兴证据表明,TNF超家族成员B淋巴细胞刺激物(BLyS),也称为(B细胞活化因子)BAFF,及其受体,尤其是BAFF-R,是正常和正常人生长和存活的关键因素。恶性B细胞。尽管最近已经广泛研究了通过BAFF-R介导的信号传导途径,但尚未阐明BAFF-R的转录调控,特别是在淋巴瘤和白血病中。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号