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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Radioactive sources embedded in suture are associated with improved postimplant dosimetry in men treated with prostate brachytherapy.
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Radioactive sources embedded in suture are associated with improved postimplant dosimetry in men treated with prostate brachytherapy.

机译：植入缝线中的放射源与接受前列腺近距离放射治疗的男性的植入后剂量测定改善有关。

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BACKGROUND AND PURPOSE: Reports using the retropubic and transperineal technique of prostate brachytherapy suggest that adequate radiation doses are required for good clinical results with I-125. After 3 years of using loose sources (LS), radioactive sources embedded in suture (SES) were introduced into our prostate brachytherapy technique. The purpose of the present report is to determine whether dosimetric quantifiers of implant adequacy were affected by the use of SES.MATERIALS AND METHODS: Between September 1999 and April 2000, 20 patients were treated with prostate brachytherapy alone with a preplanned, preloaded needle technique using LS. Between May 2000 and February 2001, 20 patients were treated with prostate brachytherapy alone with a preplanned, preloaded needle technique using SES. Dosimetric quantifiers (DQ) of implant adequacy were calculated using a computed tomography scan performed 1 month following prostate brachytherapy. DQ were compared between patients treated with LS and patients treated with SES.RESULTS: The demographic characteristics were similar for each group. Men treated with SES had slightly smaller prostate glands compared to men treated with LS. The mean total activity and activity per seed were similar for each group but the activity per unit volume was slightly higher for the SES group. Patients treated with SES were found to have significantly improved DQ compared to patients treated with LS. The mean V100 for patients treated with SES was 94.10% compared to 86.54% in those patients treated with LS (P<0.001).CONCLUSIONS: In our experience using preplanning and preloaded needles, the use of SES is associated with improved postimplant DQ.
机译：背景与目的：使用前列腺近距离放射疗法的耻骨后和会阴技术的报告表明，I-125的良好临床效果需要足够的放射剂量。使用松散源（LS）三年后，将嵌入缝合线（SES）中的放射源引入我们的前列腺近距离放射治疗技术中。本报告的目的是确定使用SES是否会影响植入物剂量的剂量学计量。材料与方法：在1999年9月至2000年4月之间，仅对20例患者进行了前列腺癌近距离放射治疗，并采用了预先计划的预加载针技术LS。在2000年5月至2001年2月之间，采用SES的预计划，预负荷针技术对20例患者单独进行了前列腺近距离放射治疗。使用前列腺近距离放射治疗后1个月进行的计算机断层扫描，计算植入物的剂量定量值（DQ）。比较接受LS治疗的患者和接受SES治疗的患者的DQ。结果：各组的人口统计学特征相似。与LS治疗的男性相比，接受SES治疗的男性的前列腺较小。每组的平均总活性和每粒种子的活性相似，但SES组的单位体积活性稍高。与LS治疗的患者相比，SES治疗的患者的DQ明显改善。 SES治疗的患者的平均V100为94.10％，而LS治疗的患者的平均V100为86.54％（P <0.001）。结论：根据我们使用预计划和预装针头的经验，SES的使用可改善植入后的DQ。

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