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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia.
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Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia.

机译:放射线引起的唾液功能障碍和口干症风险器官的描述指南。

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BACKGROUND AND PURPOSE: It is believed that minimizing inconsistencies in OAR-volume definition will help to improve adequate reporting and interpreting of radiation treatment results. The aim of this paper is to introduce computed tomography (CT)-based delineation guidelines for organs at risk (OARs) in the head and neck area, associated with radiation-induced salivary dysfunction and xerostomia. MATERIAL AND METHODS: After analyses of the human anatomy of the head and neck area, computed tomography (CT)-based guidelines for delineation of the most relevant OARs were described by a panel of experts. RESULTS AND CONCLUSIONS: The provided OAR guidelines are accompanied by CT-based illustrations presenting examples of the delineated structures and their corresponding anatomic boundaries. The parts of the tongue bearing minor salivary glands could not be outlined. Difficulties and uncertainties in defining these minor salivary glands on CT remain to be resolved. Implementation of these guidelines in practice should lead to a reduction in inter- and intra-observer variability and therefore unambiguous reporting of possible dose-volume effect relationships.
机译:背景与目的:相信最大程度地减少OAR量定义的不一致性将有助于改善对放射治疗结果的充分报道和解释。本文的目的是介绍基于计算机断层扫描(CT)的头颈部区域危险器官(OAR)的描绘指南,这些指南与放射线引起的唾液功能障碍和口腔干燥症相关。材料与方法:在对人体头部和颈部的解剖结构进行分析之后,由专家小组描述了基于计算机断层扫描(CT)来确定最相关的OAR的指南。结果与结论:所提供的OAR指南随附有基于CT的插图,这些插图显示了所描绘的结构及其相应的解剖边界的示例。舌头上带有唾液腺的部分无法勾勒出轮廓。在CT上定义这些小唾液腺的困难和不确定性仍有待解决。在实践中执行这些指南应可减少观察者之间和观察者内部的变异性,因此可以明确报告可能的剂量-体积效应关系。

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