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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Comparison of cervical esophagus dose-volumes for three radiotherapy techniques for head and neck cancer.
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Comparison of cervical esophagus dose-volumes for three radiotherapy techniques for head and neck cancer.

机译：三种头颈部癌放疗技术的宫颈食管剂量-体积比较。

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摘要

PURPOSE: This study compares the radiation dose-volume of the cervical esophagus during head and neck radiotherapy using three different techniques. METHODS: Treatment plans of 58 patients from 3/04 to 1/06 treated with bilateral head and neck radiotherapy were analyzed retrospectively. A comparison of the cervical esophagus dose with three-field 3D conformal RT (3DRT, n=34), whole-field IMRT (WF-IMRT, n=12), and half-beam IMRT (HB-IMRT, n=12) was performed. The volumes of esophagus receiving 50Gy (V50), 54Gy (V54) and 60Gy (V60) and lengths receiving circumferential dose 50Gy (L50) and 54Gy (L54) were evaluated. RESULTS: Maximum dose, V54 and L54 were greater for the first 2cm and entire cervical esophagus with WF-IMRT than HB-IMRT or 3DRT. In patients requiring a high match, WF-IMRT was associated with a greater maximum dose, V54 and L54 than HB-IMRT and 3DRT (p<0.05). In the low match group, WF-IMRT was associated with a greater V54 and L54 (p<0.05). Low neck disease, low primary site, and definitive radiotherapy were associated with increased irradiation of the esophagus. CONCLUSION: Treatment of the lower neck with IMRT is associated with increased irradiation to the cervical esophagus, and dose constraints should be included to reduce toxicity.
机译：目的：本研究比较了三种不同技术在头颈部放疗过程中宫颈食道的放射剂量。方法：回顾性分析58例3/04〜1/06双侧头颈部放疗患者的治疗方案。颈食管剂量与三场3D适形RT（3DRT，n = 34），全场IMRT（WF-IMRT，n = 12）和半光束IMRT（HB-IMRT，n = 12）的比较被执行了。评估接受50Gy（V50），54Gy（V54）和60Gy（V60）的食道的体积以及接受圆周剂量50Gy（L50）和54Gy（L54）的食道的长度。结果：WF-IMRT的前2cm和整个宫颈食管的最大剂量，V54和L54大于HB-IMRT或3DRT。在需要高度匹配的患者中，WF-IMRT与最大剂量V54和L54的相关性高于HB-IMRT和3DRT（p <0.05）。在低匹配组中，WF-IMRT与更大的V54和L54相关（p <0.05）。低颈部疾病，低原发部位和确定的放疗与食道辐射增加有关。结论：IMRT治疗下颈部会增加对宫颈食道的辐射，因此应包括剂量限制以减少毒性。

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