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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Image guided, adaptive, accelerated, high dose brachytherapy as model for advanced small volume radiotherapy.
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Image guided, adaptive, accelerated, high dose brachytherapy as model for advanced small volume radiotherapy.

机译:图像引导,自适应,加速,高剂量近距离放射治疗,作为先进的小剂量放射治疗的模型。

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摘要

Brachytherapy has consistently provided a very conformal radiation therapy modality. Over the last two decades this has been associated with significant improvements in imaging for brachytherapy applications (prostate, gynecology), resulting in many positive advances in treatment planning, application techniques and clinical outcome. This is emphasized by the increased use of brachytherapy in Europe with gynecology as continuous basis and prostate and breast as more recently growing fields. Image guidance enables exact knowledge of the applicator together with improved visualization of tumor and target volumes as well as of organs at risk providing the basis for very individualized 3D and 4D treatment planning. In this commentary the most important recent developments in prostate, gynecological and breast brachytherapy are reviewed, with a focus on European recent and current research aiming at the definition of areas for important future research. Moreover the positive impact of GEC-ESTRO recommendations and the highlights of brachytherapy physics are discussed what altogether presents a full overview of modern image guided brachytherapy. An overview is finally provided on past and current international brachytherapy publications focusing on Radiotherapy and Oncology research areas over the last three decades strongly influenced recently by translational research in regard to imaging and technology. In order to provide high level clinical evidence for future brachytherapy practice the strong need for comprehensive prospective clinical research addressing brachytherapy issues is high-lighted.
机译:近距离放射疗法一直提供非常适形的放射疗法形式。在过去的二十年中,这与近距离放射治疗(前列腺,妇科)的影像学显着改善有关,从而在治疗计划,应用技术和临床结果方面取得了许多积极进展。在欧洲,以妇科为连续基础的近距离放射疗法的使用越来越多,而最近发展中的领域则以前列腺和乳房的放射疗法越来越多地强调了这一点。图像指导使您能够准确了解涂药器,并改善肿瘤和目标体积以及处于危险状态的器官的可视化,从而为非常个性化的3D和4D治疗计划提供基础。在这篇评论中,回顾了前列腺,妇科和乳房近距离放射治疗中最重要的最新进展,重点是欧洲的最新研究和当前研究,旨在确定重要的未来研究领域。此外,还讨论了GEC-ESTRO建议的积极影响以及近距离放射疗法的重点,这些内容一起全面介绍了现代影像引导近距离放射疗法。最后概述了过去和现在的国际近距离放射治疗出版物,这些出版物着重于过去三十年来受影像和技术方面的转化研究强烈影响的放射治疗和肿瘤学研究领域。为了为将来的近距离放射治疗实践提供高水平的临床证据,提出了解决近距离放射治疗问题的全面的前瞻性临床研究的强烈需求。

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