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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Interobserver variations in gross tumor volume delineation of brain tumors on computed tomography and impact of magnetic resonance imaging.
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Interobserver variations in gross tumor volume delineation of brain tumors on computed tomography and impact of magnetic resonance imaging.

机译：在计算机断层扫描和磁共振成像的影响下脑瘤的总体肿瘤体积描绘中观察者间的差异。

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PURPOSE: (1) To assess the interobserver variability of brain tumor delineation on computed tomography (CT). (2) To assess the impact of the addition of magnetic resonance imaging (MRI) information. METHODS: Nine physicians were asked to delineate the gross tumor volume (GTV) of five patients with supratentorial inoperable brain tumors on CT scans and 2 weeks (or more) later on MRIs. The delineations were performed on a computer screen. During delineation on MRI, the registered CT images (without delineation) were displayed on the screen (MRI+CT). RESULTS: A high interobserver variability in GTV delineation on CT is found: the ratio of the largest to the smallest defined volumes varies for the five patients by factors of resp. 2.8, 1.8, 1.8, 1.9 and 1.7. The interobserver variability is as large on MRI+CT as on CT alone (ratio largest/smallest volume: 2.4, 1.7, 1.9, 2.7 and 1.5). Volumes delineated on MRI+CT (mean: 69.6 cm(3)) are larger than on CT alone (mean: 59.5 cm(3)). Residual volumes (volume delineated on one image modality but not on the other) are >0 for CT alone and for MRI+CT. CONCLUSIONS: A large interobserver variability in GTV delineation of brain tumors is demonstrated. The addition of MRI to CT does not reduce interobserver variability. GTVs delineated on MRI+CT are larger than on CT alone, but some volumes are delineated on CT and not on MRI. Therefore, a combination of the two image modalities is recommended for brain tumor delineation for treatment planning.
机译：目的：（1）评估计算机断层扫描（CT）上脑肿瘤描绘的观察者间差异。 （2）评估添加磁共振成像（MRI）信息的影响。方法：9位医生被要求在CT扫描和2周（或更长）的MRI上描绘5例幕上不能手术的脑肿瘤患者的总肿瘤体积（GTV）。所述描述在计算机屏幕上进行。在MRI描绘期间，已注册的CT图像（没有描绘）显示在屏幕上（MRI + CT）。结果：发现CT上GTV描画的观察者间差异很大：五位患者的最大定义体积与最小定义体积之比因反应因素而异。 2.8、1.8、1.8、1.9和1.7。观察者之间的变异性在MRI + CT上与在单独CT上一样大（最大/最小体积比：2.4、1.7、1.9、2.7和1.5）。在MRI + CT上描绘的体积（平均：69.6 cm（3））比在单独CT上描绘的体积（平均：59.5 cm（3））大。单独的CT和MRI + CT的残余体积（在一个图像模态上描绘的体积，而不是在另一个图像模态上描绘的体积）> 0。结论：在脑肿瘤的GTV描绘中观察者间存在较大的变异性。在CT上增加MRI不会降低观察者之间的差异。在MRI + CT上描绘的GTV大于单独在CT上描绘的GTV，但是在CT而非MRI上描绘了一些体积。因此，建议将两种图像模式结合起来用于脑肿瘤描绘，以进行治疗计划。

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