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首页> 外文期刊>Resuscitation. >Resuscitation outcomes comparing year 2000 with year 2005 ALS guidelines in a pig model of cardiac arrest.
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Resuscitation outcomes comparing year 2000 with year 2005 ALS guidelines in a pig model of cardiac arrest.

机译：在心脏骤停的猪模型中比较2000年和2005年ALS指南的复苏结果。

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摘要

BACKGROUND: Ventricular fibrillation remains the leading cause of death in western societies. International organizations publish guidelines to follow in case of cardiac arrest. The aim of the present study is to assess whether the newly published guidelines record similar resuscitation success with the 2000 Advanced Life Support Guidelines on Resuscitation in a swine model of cardiac arrest. METHODS AND RESULTS: Nineteen landrace/large white pigs were used. Ventricular fibrillation was induced with the use of a transvenous pacing wire inserted into the right ventricle. The animals were randomized into two groups. In Group A, 10 animals were resuscitated using the 2000 guidelines, whereas in Group B, 9 animals were resuscitated using the 2005 guidelines. Both algorithms recorded similar successful resuscitation rates, as 60% of the animals in Group A and 44.5% in Group B were successfully resuscitated. However, animals in Group A restored a rhythm, compatible with a pulse, quicker than those in Group B(p=0.002). Coronary perfusion pressure (CPP) was not adversely affected by three defibrillation attempts in Group A. CONCLUSIONS: Both algorithms' resulted in comparable resuscitation success, however, guidelines 2000 resulted in faster resuscitation times. These preliminary results merit further investigation.
机译：背景：心室纤颤仍然是西方社会死亡的主要原因。国际组织发布了心脏骤停时要遵循的指南。本研究的目的是评估新发布的指南是否在心脏骤停的猪模型中记录了与2000年《高级生命支持复苏指南》相似的复苏成功。方法和结果：使用了十九只地方品种/大型白猪。使用插入右心室的静脉起搏线诱发心室纤颤。将动物随机分为两组。在A组中，使用2000年指南复苏了10只动物，而在B组中，在2005年指南中复苏了9只动物。两种算法均记录了相似的成功复苏率，因为A组60％的动物和B组44.5％的动物被成功复苏。然而，与B组相比，A组的动物恢复了与脉搏相适应的节律（p = 0.002）。在A组中进行了3次除纤颤尝试，未对冠脉灌注压（CPP）产生不利影响。结论：两种算法均在复苏方面取得了可比的成功，但是，准则2000却加快了复苏时间。这些初步结果值得进一步调查。

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