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首页> 外文期刊>Rhinology >Olfactory performance of patients with anorexia nervosa and healthy subjects in hunger and satiety.
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Olfactory performance of patients with anorexia nervosa and healthy subjects in hunger and satiety.

机译：神经性厌食症患者和健康受试者在饥饿和饱腹中的嗅觉表现。

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摘要

The aim of this study was to compare the olfactory performance of anorectic patients and healthy controls with regard to the state of satiety. Using the Sniffin' Sticks, sensitivity to a nonfood odor (n-butanol) and to a food-related odor (isoamyl acetate) was assessed in 12 anorectic females and compared with 24 healthy controls. Threshold tests were performed in a hungry as well as in a satiated state, odor discrimination and odor identification only when satiated. Pleasantness of the odors was recorded. In terms of the non-food odor n-butanol, the olfactory sensitivity of anorectic patients and controls did not differ. Patients with anorexia nervosa had a significantly lower detection threshold for the food-related odor, but only in the hungry condition. Anorectic patients showed significant deficits in odor discrimination and identification, and under-evaluated the pleasantness of isoamyl acetate. Our results suggest an impaired projection from secondary to tertiary olfactory structures in anorexianervosa, based upon the dichotomy of performance between detection threshold and odor discrimination/dentification. The reduced pleasantness of isoamyl acetate indicates a decreased olfactory responsiveness to food stimuli in anorexia nervosa.
机译：这项研究的目的是就饱腹感比较厌食症患者和健康对照者的嗅觉表现。使用嗅探棒，评估了12名厌食女性对非食物气味（正丁醇）和食物相关气味（乙酸异戊酯）的敏感性，并与24名健康对照者进行了比较。在饥饿状态以及饱足状态下进行阈值测试，仅在饱足状态下才进行气味识别和气味识别。记录气味的宜人性。就非食用气味正丁醇而言，厌食症患者和对照组的嗅觉敏感性没有差异。神经性厌食症患者的食物相关气味的检测阈值明显较低，但仅在饥饿状态下。厌食患者表现出明显的气味识别和鉴别缺陷，并且低估了乙酸异戊酯的舒适度。我们的结果表明，基于检测阈值与气味识别/识别之间的性能二分法，神经性厌食症的二级至三级嗅觉结构的投影受损。乙酸异戊酯的愉悦度降低表明神经性厌食症对食物刺激的嗅觉响应性降低。

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