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首页> 外文期刊>Rheumatology >Assessing structural changes in axial spondyloarthritis using a low-dose biplanar imaging system
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Assessing structural changes in axial spondyloarthritis using a low-dose biplanar imaging system

机译：使用低剂量双平面成像系统评估轴向性脊柱关节炎的结构变化

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Objectives: Patients with axial SpA experience repeated spine imaging. EOS is a new low-dose imaging system with significantly lower irradiation than conventional radiography (CR). The objective was to explore the EOS performances compared with CR for the classification and follow-up of SpA. Methods: We performed an observational, cross-sectional, single-centre study including SpA patients (definite diagnosis by expert opinion) and control patients [definite chronic mechanical low back pain (cLBP)]. All patients underwent pelvic and frontal and lateral CR of the entire spine and twodimensional (2D) EOS imaging on the same day. Images were blindly assessed for sacroiliitis [modified New York criteria (mNY)] and for ankylosis of the spine [modified Stoke AS Spine Score (mSASSS)]. Global ease of interpretation was rated on a scale of 0-10. The primary outcome was intermodality agreement, with an a priori defined non-inferiority limit of 0.7. Interobserver, intra-observer and intermodality agreement were measured by kappa, weighted kappa, intraclass correlation coefficient and Bland-Altman plots. Results. Forty-eight SpA patients [mean age 47.6 years (S.D. 14.9), symptom duration 21.4 years (S.D. 13.3), 35 (70%) men] and 48 cLBP controls [mean age 49.1 years (S.D. 10.7), 9 (22.5%) men] were included. Intermodality agreement between EOS and CR was 0.50 (95% CI 0.26, 0.75) and 0.97 (95% CI 0.95, 0.98) for sacroiliitis and mSASSS, respectively. Ease of interpretation was greater for CR [8.2 (S.D. 0.9)] compared with EOS [7.2 (S.D. 0.8), P<0.0001). Conclusion: Our results suggest that EOS could replace CR for the follow-up of structural damage of the spine, but its place in the classification of sacroiliitis needs to be further explored.
机译：目的：患有轴向SpA的患者会反复进行脊柱成像。 EOS是一种新型的低剂量成像系统，其辐射远低于常规放射线照相（CR）。目的是探索与CR相比EOS的性能，以对SpA进行分类和跟踪。方法：我们进行了一项观察性，横断面，单中心研究，包括SpA患者（专家意见明确诊断）和对照患者[明确的慢性机械性下背痛（cLBP）]。所有患者均在同一天接受整个脊柱的骨盆，额叶和外侧CR以及二维（2D）EOS成像。盲目评估图像的sa肌炎[修改后的纽约标准（mNY）]和脊柱强直[修改后的Stoke AS脊柱评分（mSASSS）]。总体解释的方便程度为0-10。主要结果是多式联运协议，事先定义的非劣性极限为0.7。观察者之间，观察者内部和模态一致性通过卡伯，加权卡伯，类内相关系数和布兰德-奥特曼图进行测量。结果。 48名SpA患者[平均年龄47.6岁（SD 14.9），症状持续时间21.4岁（SD 13.3），35（70％）男性]和48 cLBP对照[平均年龄49.1岁（SD 10.7），9（22.5％）男子]。 sa关节炎和mSASSS的EOS和CR之间的联运协议分别为0.50（95％CI 0.26，0.75）和0.97（95％CI 0.95，0.98）。与EOS [7.2（S.D. 0.8），P <0.0001）相比，CR [8.2（S.D. 0.9）]易于解释。结论：我们的结果表明EOS可以代替CR来治疗脊柱结构性损伤，但在in关节炎分类中的地位还有待进一步探讨。

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