...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Occupational and environmental medicine >Organochlorine compounds and thyroid dysfunction in children: is there a link with neurotoxicity?
【24h】

Organochlorine compounds and thyroid dysfunction in children: is there a link with neurotoxicity?

机译：儿童的有机氯化合物和甲状腺功能异常：与神经毒性有联系吗？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Recent epidemiological and experimental studies have suggested that persistent organochlorine compounds (OCs) such as polychiorinated biphenyls (PCBs) and dioxins may alter thyroid hormone levels in animals and humans. As neurological development occurs in discrete developmental windows, even transient disorders in thyroid hormone availability can have profound effects on brain development.1 Most studies have focused on the effects of prenatal exposure, but little evidence exists concerning the effects of exposure to OCs during childhood.Further research on the latter is reported in a paper by Alvarez-Pedrerol et al in this issue. Exposure to certain OCs such as dichlorodiphenyl trichloroethane(p,p'-DDT), beta-hexachlorocylcohexane(beta-HCH) and polychiorinated biphenyls (congeners PCB-138, PCB-153 and PCB-118) was related to lower total T3 levels in preschool children on the island of Menorca in Spain.
机译：最近的流行病学和实验研究表明，持久性有机氯化合物（OC）（例如多氯联苯（PCB）和二恶英）可能会改变动物和人类的甲状腺激素水平。由于神经系统发育发生在离散的发育窗口中，即使甲状腺激素利用率的暂时性紊乱也可能对大脑发育产生深远的影响。1大多数研究都集中在产前暴露的影响上，但很少有证据表明儿童时期暴露于OCs。 Alvarez-Pedrerol等人在本期的一篇论文中报道了对后者的进一步研究。接触某些OC（例如二氯二苯基三氯乙烷（p，p'-DDT），β-六氯环己烷（beta-HCH）和多氯联苯（同类PCB-138，PCB-153和PCB-118））与降低T3中的总T3水平有关西班牙梅诺卡岛上的学龄前儿童。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号