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Review of recent epidemiological studies on paternal occupations and birth defects.

机译:近期关于父亲职业和出生缺陷的流行病学研究综述。

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摘要

The main findings reported by recent epidemiological studies on paternal occupations and birth defects are reviewed, and the main limitations associated with these studies discussed. Epidemiological studies on paternal occupations and birth defects were reviewed for the period 1989 to 1999 inclusive. Systematic searches were made with search engines with related keywords. There were several common paternal occupations that were repeatedly reported to be associated with birth defects. These paternal occupations were janitors, painters, printers, and occupations exposed to solvents; fire fighters or firemen; and occupations related to agriculture. The common weaknesses in most of these studies include inaccurate assessment of exposures, different classification systems, different inclusion criteria of birth defects, and low statistical power. It is concluded that epidemiological studies, reported in the past decade, suggest that several common paternal occupations are associated with birth defects. Future studies could be focused on these specific, rather than general, occupational groups so that causative agents may be confirmed and thus enable appropriate preventive measures to be taken.
机译:对最近流行病学研究报告的有关父亲职业和出生缺陷的主要发现进行了综述,并讨论了与这些研究相关的主要局限性。审查了有关父亲职业和出生缺陷的流行病学研究,调查期间为1989年至1999年。使用带有相关关键字的搜索引擎进行系统搜索。有几次常见的父亲职业被反复报道与出生缺陷有关。这些父亲的职业是管理员,油漆工,印刷工人以及暴露于溶剂中的职业。消防员或消防员;与农业有关的职业。这些研究大多数的共同弱点包括对暴露的评估不正确,分类系统不同,出生缺陷的纳入标准不同以及统计能力低。结论是,在过去的十年中进行的流行病学研究表明,几种常见的父亲职业与出生缺陷有关。未来的研究可能会集中在这些特定的而非一般的职业人群上,以便确定致病因素,从而采取适当的预防措施。

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