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首页> 外文期刊>Occupational and environmental medicine >Effects of maternal exposure to cadmium on pregnancy outcome and breast milk.
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Effects of maternal exposure to cadmium on pregnancy outcome and breast milk.

机译：孕妇接触镉对妊娠结局和母乳的影响。

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OBJECTIVE: The effects of cadmium (Cd) on birth weight have been discussed in the scientific literature. However, investigations on the effects of maternal body burden of Cd on the next generation during pregnancy and lactation have been limited. The relation between maternal exposure to Cd and pregnancy outcome or Cd in breast milk in Japanese mothers was investigated. METHODS: Cd concentrations in urine and colostrum milk samples of 57 mothers were measured by atomic absorption spectrophotometery. The relations between maternal urinary Cd and infant growth, gestational age at birth, and Cd in breast milk were investigated. RESULTS: The rate of perterm deliveries of mothers with higher urinary Cd (>/=2 nmol/mmol creatinine (Cr)) was higher than that of mothers with lower urinary Cd (<2 nmol/mmol Cr). The gestational age was significantly correlated with urinary Cd even after adjustment for maternal age. The height and weight of newborn infants of mothers with higher urinary Cd were significantly lower than those of the newborn infants of mothers with lower urinary Cd, but these decreases were ascribed to early delivery induced by Cd. The Cd in breast milk of mothers with higher urinary Cd was significantly higher than that of mothers with lower urinary Cd. A significant positive correlation was found between maternal urinary Cd and Cd in breast milk. CONCLUSION: Maternal exposure to Cd seems to increase early delivery, which leads to a lower birth weight. Also, the Cd is transferred in part to the next generation through breast milk after birth.
机译：目的：科学文献已经讨论了镉对出生体重的影响。然而，关于孕妇和哺乳期镉对孕妇的机体负担对下一代影响的研究仍然有限。研究了日本母亲的母亲接触Cd与妊娠结局或母乳中Cd之间的关系。方法：采用原子吸收分光光度法测定了57名母亲的尿液和初乳中的镉含量。研究了孕妇尿中镉与婴儿生长，出生时的胎龄和母乳中镉的关系。结果：尿镉较高（> / = 2 nmol / mmol肌酐（Cr））的母亲的足月分娩率高于尿镉较低（<2 nmol / mmol Cr）的母亲的足月分娩率。即使调整了产妇年龄，胎龄也与尿镉显着相关。尿镉含量较高的母亲的新生婴儿的身高和体重显着低于尿镉含量较低的母亲的新生婴儿的身高和体重，但这些下降归因于镉引起的早产。尿镉含量较高的母亲的母乳中的镉含量明显高于尿镉含量较低的母亲。母乳中的镉和母乳中的镉之间存在显着的正相关。结论：孕妇接触Cd似乎会增加早期分娩，从而降低出生体重。而且，镉在出生后会通过母乳部分转移到下一代。

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