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首页> 外文期刊>Occupational and environmental medicine >Trends in blood lead levels in UK workers, 1995-2007.
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Trends in blood lead levels in UK workers, 1995-2007.

机译：1995-2007年英国工人的血铅水平趋势。

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OBJECTIVES: This study evaluated blood lead data (including zinc protoporphyrin (ZPP) and haemoglobin levels) collected at the UK's Health and Safety Laboratory (HSL) in order to determine temporal changes in occupational exposure to lead between 1995 and 2007. METHODS: A total of 20,889 blood lead measurements and accompanying ZPP and haemoglobin results from 8810 workers at 972 companies from routine samples received by HSL over the period 1995-2007 were analysed. Time trends in blood lead levels for each industry sector were estimated using Bayesian mixed effects modelling. RESULTS: Reductions in median blood levels over the period 1995-2007 were seen in every sector except for those samples forwarded by occupational health providers, and range from 1.6% per year for workers in the smelting industry to 12% per year for workers in pottery and glazing industries. An overall reduction of 3.1% per year across all industries was determined. The percentage of results above the current UK suspension limit of 60 microg/dl fell from 4.8% in 1995 to 0.6% in 2007. ZPP and blood lead exhibited a strong association, but no significant correlation was found between blood lead and haemoglobin. CONCLUSIONS: Occupational exposure to lead has fallen across UK industries in recent years, although it remains substantially above background levels. There is evidence that many workers are exposed to elevated lead levels over a long period of time and this deserves renewed consideration now that inorganic lead has been reclassified as a probable human carcinogen.
机译：目的：本研究评估了英国健康与安全实验室（HSL）收集的血铅数据（包括锌原卟啉（ZPP）和血红蛋白水平），以确定1995年至2007年期间铅职业暴露的时间变化。方法：总计分析了1995年至2007年期间HSL收到的常规样品中20 889份血铅测量值，以及来自972家公司8810名工人的ZPP和血红蛋白结果。使用贝叶斯混合效应模型估算了每个行业的血铅水平的时间趋势。结果：除职业健康提供者转发的样本外，各个部门的血液中位数水平在1995年至2007年期间均出现下降，范围从冶炼行业的工人的每年1.6％到陶艺工人的每年12％。和玻璃工业。已确定所有行业每年整体减少3.1％。超过当前英国悬浮液限值60 microg / dl的结果百分比从1995年的4.8％下降到2007年的0.6％。ZPP和血铅显示出很强的相关性，但是血铅和血红蛋白之间没有显着相关性。结论：近年来，尽管整个行业的铅暴露水平仍大大高于本底水平，但其在铅行业中的铅暴露水平有所下降。有证据表明，许多工人长期处于高水平的铅暴露之下，鉴于无机铅已被重新归类为可能的人类致癌物，因此值得重新考虑。

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