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首页> 外文期刊>Occupational and environmental medicine >Road traffic and adverse respiratory effects in children. SIDRIA Collaborative Group.
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Road traffic and adverse respiratory effects in children. SIDRIA Collaborative Group.

机译:道路交通和对儿童的不利呼吸作用。 SIDRIA合作小组。

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OBJECTIVES: To investigate the relation between traffic indicators in the area of residence and the occurrence of chronic respiratory disorders in children. METHODS: A population based survey was conducted in 10 areas of northern and central Italy (autumn 1994 to winter 1995) in two age groups (6-7 and 13-14 years). Information on several respiratory disorders and on traffic near residences was collected with a questionnaire given to children and to their parents. The sample analysed included 39,275 subjects (response rate 94.4%). Outcomes were: (a) early (first 2 years of life) respiratory diseases, and (b) current respiratory disorders (asthma, wheeze, cough, or phlegm in the past year). Odds ratios (ORs) and 95% confidence intervals (95% CIs), adjusted for several potential confounders, were estimated from logistic regression models. Main results were stratified by level of urbanisation (metropolitan areas, other centres). RESULTS: In the metropolitan areas, high frequency of lorry traffic in the street of residence was associated with significantly increased risks for many adverse respiratory outcomes. Among early respiratory diseases, the strongest associations were found for recurrent bronchitis (OR 1.69, 95% CI 1.24 to 2.30), bronchiolitis (1.74, 1.09 to 2.77) and pneumonia (1.84, 1.27 to 2.65), although no association was detected for episodes of wheezing bronchitis. All the current respiratory disorders were positively and consistently associated with frequency of lorry traffic, particularly the most severe bronchitic and wheezing symptoms: persistent phelgm for > 2 months (1.68; 1.14 to 2.48), and severe wheeze limiting speech (1.86; 1.26 to 2.73). No or weaker associations with heavy vehicular traffic were detected in urban and rural areas and no increased risks were found in the whole sample with the reported traffic density in the zone of residence. After extensive evaluations, the potential of reporting bias seems unlikely. CONCLUSION: Exposure to exhausts from heavy vehicular traffic may have several adverse effects on respiratory health of children living in metropolitan areas, increasing the occurrence of lower respiratory tract infections early in life and of wheezing and bronchitic symptoms at school age.
机译:目的:探讨居住区交通指标与儿童慢性呼吸系统疾病发生率之间的关系。方法:在意大利北部和中部(1994年秋季至1995年冬季)的10个地区进行了基于人群的调查,分为两个年龄段(6-7岁和13-14岁)。收集了有关儿童及其父母的问卷,收集了有关几种呼吸系统疾病和住所附近交通的信息。分析的样本包括39,275名受试者(回应率为94.4%)。结果为:(a)早期(生命的前2年)呼吸道疾病,以及(b)当前的呼吸系统疾病(在过去一年中出现哮喘,喘息,咳嗽或痰)。根据对数回归模型,对几项潜在的混杂因素进行了调整后,几率(OR)和95%置信区间(95%CI)得以估计。主要结果按城市化水平(大都市区,其他中心)进行了分层。结果:在大都市地区,居住街道上的货车运输频繁与许多不良呼吸道结局的风险显着增加有关。在早期呼吸系统疾病中,与复发性支气管炎(OR 1.69,95%CI 1.24至2.30),细支气管炎(1.74、1.09至2.77)和肺炎(1.84、1.27至2.65)相关性最强,尽管未发现相关性喘息性支气管炎。当前所有呼吸系统疾病均与卡车运输频率呈正相关,并始终如一,尤其是最严重的支气管和喘息症状:持续性咽> 2个月(1.68; 1.14至2.48),以及严重的喘息限制言语(1.86; 1.26至2.73) )。在城市和农村地区,未发现与交通拥堵的关联性较弱或较弱,并且在报告的居住区域内交通密度较高的整个样本中,未发现风险增加。经过广泛的评估,报告偏差的可能性似乎很小。结论:交通繁忙的尾气暴露可能会对居住在大都市地区的儿童的呼吸系统健康产生若干不利影响,从而增加生命早期下呼吸道感染的发生率以及学龄时的喘息和支气管症状。

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