Radium-223 vs EBRT for multiple painful bone metastases: Is less more?

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Radium-223 vs EBRT for multiple painful bone metastases: Is less more?

机译：Radium-223与EBRT可以治疗多种疼痛的骨转移瘤：少得多吗？

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There is no question that radiopharma-ceuticals have a role in the management of patients with metastatic bone disease. [1,2] There is also no question that fractionated external beam radiotherapy (EBRT) is highly effective and generally well tolerated when delivered with large open or focal fields. [3] The answer to the question of which form of treatment is preferred should be based on: relative effectiveness, availability, and cost. [4]

机译：毫无疑问，放射性药物在转移性骨病患者的治疗中具有重要作用。 [1,2]毫无疑问，分段大剂量放射治疗（EBRT）在大视野或大视野范围内进行治疗时，效果很好，并且通常具有良好的耐受性。 [3]首选哪种治疗形式的答案应基于：相对有效性，可获得性和成本。 [4]

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《Oncology》 |2014年第4期|共2页
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1. Radium-223 vs EBRT for multiple painful bone metastases: The data favor radium-223 [J] . Oncology . 2014,第4期

机译：Radium-223 vs EBRT可治疗多种疼痛的骨转移：数据偏向镭223
2. A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer [J] . NilssonS., StrangP., AksnesA.K., European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2012,第5期

机译：一项随机，剂量反应，多中心II期研究，研究镭223氯化物对去势抵抗性前列腺癌患者疼痛性骨转移的缓解作用
3. 1277 POSTER Quality of life in patients with painful bone metastases: results from the randomized dutch bone metastasis study on single fraction versus multiple fraction radiotherapy [J] . European Journal of Cancer Supplements . 2005,第2期

机译：1277 POSTER疼痛性骨转移患者的生活质量：单次放疗与多次放疗的荷兰荷兰骨转移随机研究结果
4. Bone pain therapies in patients with multiple bone metastases using Re- 188-HEDP [C] . The First China-Japan-Korea conference of nuclear medicine . 2002

机译：使用Re-188-HEDP对多发性骨转移患者进行骨痛治疗
5. The role of adrenomedullin in osteolytic breast cancer bone metastases. [D] . Siclari, Valerie Anne. 2009

机译：肾上腺髓质素在溶骨性乳腺癌骨转移中的作用。
6. Progression to bone-marrow carcinomatosis and extraosseous legion during treatment with radium-223 for multiple bone metastases [O] . Takahiko Hajime, Masaki Shiota, Tatsuro Abe, 2018

机译：镭223治疗多发性骨转移期间进展为骨髓癌和骨外军团
7. A randomized, dose–response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer [O] . Nilsson S., Strang P., Aksnes A.K., 2012

机译：一项随机，剂量反应，多中心II期临床研究223镭对缓解去势抵抗性前列腺癌患者疼痛的骨转移的缓解作用

Radium-223 vs EBRT for multiple painful bone metastases: Is less more?

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