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首页> 外文期刊>Ophthalmology >Comparison of Pentacam and Orbscan IIz on posterior curvature topography measurements in keratoconus eyes.
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Comparison of Pentacam and Orbscan IIz on posterior curvature topography measurements in keratoconus eyes.

机译：Pentacam和Orbscan IIz在圆锥角膜后弯曲度测量中的比较。

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摘要

PURPOSE: To compare the measurements of posterior elevation above the best-fit sphere and of pachymetry in established keratoconus patients using 2 different technologies--Scheimpflug imaging with the Pentacam and scanning slit combined with Placido imaging with Orbscan IIz. DESIGN: Retrospective comparative case series. PARTICIPANTS: Patients with confirmed keratoconus by biomicroscopy and Placido topography who had corneal topography scans by the Pentacam and Orbscan IIz on their visit from April 2004 to April 2005. These scans were obtained routinely for patient diagnosis, treatment, and progression. METHODS: The mean difference, standard deviation (SD), and 95% limits of agreement (LOA) were calculated, and Bland-Altman plots were constructed for best-fit sphere radius of curvature, posterior elevation above the best-fit sphere, and pachymetry of the thinnest point. RESULTS: Thirty-six eyes of 29 patients were analyzed. The average radius for posterior best-fit sphere was 5.97 microm (range, 4.69-6.79) for the Pentacam and 6.00 microm (range, 4.97-6.55) for Orbscan IIz. The mean difference (Pentacam - Orbscan IIz) for the radius generated for the best-fit sphere was -0.03+/-0.22 SD with a 95% confidence interval (CI) of -0.11 to 0.04 and a 95% LOA of -0.46 to 0.40 (P = 0.362). The mean posterior elevation by best-fit sphere fixed to the apex was 34.86 microm (range, 3-120) for the Pentacam and 48.50 microm (range, 11-118) for Orbscan IIz. The mean difference was -13.64+/-26.08 SD (95% CI, -22.46 to -4.81; 95% LOA, -64.75 to 37.48; P = 0.003). The average thinnest point for the Pentacam was 443.6 microm (range, 164-587), and that for Orbscan IIz was 445.9 microm (range, 204-597). The mean difference in the thinnest point for the Pentacam and Orbscan IIz was -2.28+/-35.55 (95% CI, -14.31 to 9.75; 95% LOA, -71.95 to 67.39; P = 0.703). CONCLUSION: Both the Pentacam and Orbscan IIz determine similar thinnest points but have a measurable difference in posterior elevations above the best-fit sphere, despite similar radii of curvature. This difference may be important in the screening of patients for refractive surgery to avoid surgery on patients with early keratoconus. This study cannot determine if the Pentacam is underestimating the posterior vault or if Orbscan is overestimating this height, and further studies with a standardized test object are needed.
机译：目的：比较使用两种不同技术对既定圆锥角膜患者的最合适球体后高程和测厚法进行测量的方法-使用Pentacam的Scheimpflug成像和使用Orbscan IIz的Placido成像相结合的扫描狭缝成像。设计：回顾性比较案例系列。参与者：2004年4月至2005年4月，在通过生物显微镜和Placido地形图确诊圆锥角膜的患者中，Pentacam和Orbscan IIz进行了角膜地形图扫描。这些扫描是常规获得的，用于患者的诊断，治疗和进展。方法：计算平均差，标准差（SD）和95％的一致性极限（LOA），并构建Bland-Altman图以得出最佳拟合球的曲率半径，高于最佳拟合球的后仰角，以及最薄点的测厚法。结果：对29例患者的36只眼进行了分析。对于Pentacam，后最佳拟合球的平均半径为5.97微米（范围4.69-6.79），对于Orbscan IIz，其平均半径为6.00微米（范围4.97-6.55）。最佳拟合球体产生的半径的平均差（Pentacam-Orbscan IIz）为-0.03 +/- 0.22 SD，95％置信区间（CI）为-0.11至0.04，95％LOA为-0.46至0.40（P = 0.362）。对于Pentacam，固定在根尖上的最合适球体的平均后仰高度为34.86微米（范围3-120），对于Orbscan IIz为48.50微米（范围11-118）。平均差异为-13.64 +/- 26.08 SD（95％CI，-22.46至-4.81; 95％LOA，-64.75至37.48; P = 0.003）。 Pentacam的平均最薄点为443.6微米（范围164-587），而Orbscan IIz的平均最薄点为445.9微米（范围204-597）。 Pentacam和Orbscan IIz的最薄点的平均差为-2.28 +/- 35.55（95％CI，-14.31至9.75; 95％LOA，-71.95至67.39; P = 0.703）。结论：尽管曲率半径相似，但Pentacam和Orbscan IIz都确定了相似的最薄点，但在最合适球体上方的后仰角上有可测量的差异。这种差异对于筛查屈光手术的患者可能很重要，以避免对患有圆锥角膜的患者进行手术。这项研究无法确定Pentacam是否低估了后穹ault或Orbscan是否高估了这个高度，因此需要对标准化测试对象进行进一步研究。

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