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首页> 外文期刊>Optics Letters >Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow
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Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow

机译:多普勒标准差成像用于体内人体皮肤血流的临床监测

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摘要

We used a novel phase-resolved optical Doppler tomographic (ODT) technique with very high flow-velocity sensitivity (10 μm/s) and high spatial resolution (10 μm) to image blood flow in port-wine stain (PWS) birthmarks in human skin. In addition to the regular ODT velocity and structural images, we use the variance of blood flow velocity to map the PWS vessels. Our device combines ODT and therapeutic systems such that PWS blood flow can be monitored in situ before and after laser treatment. To the authors'knowledge this is the first clinical application of ODT to provide a fast semiquantitative evaluation of the efficacy of PWS laser therapy in situ and in real time.
机译:我们使用新型的相位分辨光学多普勒断层扫描(ODT)技术,具有很高的流速敏感性(10μm/ s)和高空间分辨率(10μm)来成像人口酒染色(PWS)胎记中的血流皮肤。除了常规的ODT速度和结构图像之外,我们还使用血流速度的方差来绘制PWS血管。我们的设备结合了ODT和治疗系统,因此可以在激光治疗之前和之后就地监测PWS血流。对作者而言,这是ODT的首次临床应用,它可以对PWS激光治疗的原位和实时效果进行快速的半定量评估。

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