...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Oral oncology >Impact of elective neck dissection on regional recurrence and survival in cN0 staged oral maxillary squamous cell carcinoma
【24h】

Impact of elective neck dissection on regional recurrence and survival in cN0 staged oral maxillary squamous cell carcinoma

机译：择期颈淋巴清扫术对cN0分期口腔上颌鳞癌区域复发和生存的影响

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

To evaluate the impact of elective neck dissection (END) on regional recurrence and survival in cN0 staged patients with maxillary squamous cell carcinoma (SCC). Eighty-six patients with maxillary SCC and clinically staged N0 cervical lymph-nodes were evaluated in this single center retrospective study. Seventy-four of 86 patients were included in this analysis, of which 36 patients were treated with END, 38 without END. Following END, pathohistologically verified regional lymph-nodes in the initially cN0 neck were found in three (8%) patients. In both the +END and non-END group regional recurrences occurred exclusively in patients with T4 primaries. The overall regional recurrence rate was 17% in the +END and 18% in the non-END group, respectively. The 5-year overall survival rate for all tumor stages combined (T1-T4) was 86% in the +END group and 82% in the -END group. Within the patients groups with T4 tumors, 5-year overall survival was 81% for the +END group and 56% for the -END group. Over all tumor stages combined (T1-T4), END did not significantly improve overall survival rates and did not prevent the rate of regional recurrence in cN0 staged patients with maxillary alveolar, gingival and palatal SCC. However, in the subgroup of patients with locally advanced T4 tumors, their seemed to be a clear tendency towards improvement of overall survival in the END group. END can therefore be recommended for these patients.
机译：为了评估选择性颈清扫术（END）对cN0分期上颌鳞状细胞癌（SCC）患者局部复发和生存的影响。在该单中心回顾性研究中评估了86例上颌SCC和临床分期N0颈淋巴结的患者。该分析包括86例患者中的74例，其中36例接受END治疗，38例未经END治疗。 END后，在三名（8％）患者中发现了最初cN0颈部经过病理组织学验证的区域淋巴结。在+ END和非END组中，仅在T4原发患者中发生区域性复发。 + END组和非END组的整体区域复发率分别为17％和18％。 + END组所有肿瘤分期（T1-T4）的5年总生存率分别为86％和-END组82％。在患有T4肿瘤的患者组中，+ END组的5年总生存率为81％，-END组的5年总生存率为56％。在所有肿瘤分期（T1-T4）中，END均未显着提高cN0分期上颌牙槽，牙龈和lat SCC患者的总生存率，也无法阻止区域复发率。然而，在局部晚期T4肿瘤患者亚组中，END组似乎有明显的总体生存改善趋势。因此可以为这些患者推荐END。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号