Spontaneous pain is reduced by conditioning pain modulation in peripheral neuropathy but not in fibromyalgia-Implications for different pain mechanisms

Eva Kosek

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Spontaneous pain is reduced by conditioning pain modulation in peripheral neuropathy but not in fibromyalgia-Implications for different pain mechanisms

机译：通过调节周围神经病中的疼痛调节而不是纤维肌痛来减轻自发性疼痛-对不同疼痛机制的影响

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The International Association for the Study of Pain (IASP) has recently redefined neuropathic pain as "pain caused by a lesion or disease of the somatosensory system', thereby excluding conditions with nervous system dysfunctions, such as fibromyalgia [1]. Although problematic, since neuropathic pain is rarely related to the degree of lesion or disease and rather depends on the resulting dysfunction in the nervous system, the decision can be rational given the ever increasing amount of evidence of aberrant pain modulation, i.e., somatosensory dysfunction, in various nocicep-tive pain conditions without any known lesions or diseases of the somatosensory system.

机译：国际疼痛研究协会（IASP）最近将神经性疼痛重新定义为“由躯体感觉系统的病变或疾病引起的疼痛”，从而排除了具有神经系统功能障碍的疾病，例如纤维肌痛[1]。神经性疼痛很少与病变或疾病的程度有关，而是取决于神经系统所导致的功能障碍，鉴于越来越多的异常疼痛调节的证据，即体感功能障碍，在各种夜觉中，这一决定是合理的。运动性疼痛状况，而没有任何体感系统的已知病变或疾病。

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《Scandinavian journal of pain》 |2012年第3期|共3页
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Eva Kosek;
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中图分类临床医学;
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1. Spontaneous pain is reduced by conditioning pain modulation in peripheral neuropathy but not in fibromyalgia-Implications for different pain mechanisms [J] . Eva Kosek Scandinavian journal of pain . 2012,第3期

机译：通过调节周围神经病中的疼痛调节而不是纤维肌痛来减轻自发性疼痛-对不同疼痛机制的影响
2. Cellular mechanisms of hyperalgesia and spontaneous pain in a spinalized rat model of peripheral neuropathy: changes in myelinated afferent inputs implicated. [J] . Pitcher GM, Henry JL The European Journal of Neuroscience . 2000,第6期

机译：周围神经病变的脊髓大鼠模型中的痛觉过敏和自发性疼痛的细胞机制：牵连的髓鞘传入输入的变化。
3. Conditioning pain modulation reduces pain only during the first stimulation of the?temporal summation of pain paradigm in healthy participants [J] . Holden Sinead, Petersen Kristian Kj?r, Arendt‐Nielsen Lars, European journal of pain : . 2019,第7期

机译：调节疼痛调制只会在第一次刺激健康参与者中疼痛范式的时间总结时减少疼痛
4. Efective adjuvant treatment of neuropathic pain in peripheral neuropathy by acupuncture [C] . Schroeder S, Epplee S International Congress on Neuropathic Pain . 2010

机译：针刺治疗周围神经病变神经性疼痛的有效辅助治疗
5. African Americans show alterations in endogenous pain regulatory mechanisms and reduced pain tolerance to experimental pain procedures. [D] . Mechlin, Beth. 2006

机译：非裔美国人显示出内源性疼痛调节机制发生改变，并且对实验性疼痛程序的耐受性降低。
6. Efficient conditioned pain modulation despite pain persistence in painful diabetic neuropathy [O] . Yelena Granovsky, Hadas Nahman-Averbuch, Mogher Khamaisi, 2017

机译：尽管疼痛持续存在于糖尿病性神经病中但有效的条件性疼痛调节
7. Efficient conditioned pain modulation despite pain persistence in painful diabetic neuropathy [O] . Yelena Granovsky, Hadas Nahman-Averbuch, Mogher Khamaisi, 2017

机译：尽管疼痛持续存在于疼痛性糖尿病神经病变中，但仍有效调节疼痛

Spontaneous pain is reduced by conditioning pain modulation in peripheral neuropathy but not in fibromyalgia-Implications for different pain mechanisms

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