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首页> 外文期刊>Scandinavian journal of infectious diseases. >Invasive pneumococcal infections in Southwestern Sweden: a second follow-up period of 15 years.
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Invasive pneumococcal infections in Southwestern Sweden: a second follow-up period of 15 years.

机译：瑞典西南部的侵袭性肺炎球菌感染：第二次随访期为15年。

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摘要

In a retrospective study, the incidence, clinical manifestations, concomitant conditions and case fatality rate were studied in patients with invasive pneumococcal infections in the Goteborg area of Sweden during 1981-95, when the pneumococcal polysaccharide vaccine was available but little used. Patients were identified from the records of the Departments of Clinical Bacteriology and from the computer-based hospital discharge registers of the relevant departments. Individual case records were found for 876 patients with invasive pneumococcal infections verified by cultures from blood, cerebrospinal fluid or other sterile body fluids. A study from the same area with the same design covering the years 1964-80 has previously been published. There was an increase in total incidence from 5.3 to 10.3 cases/100,000/y from the previous to the present study. This increase was due to an increase in patients with non-meningitic infections aged > or = 60 y. The incidence of meningitis was virtually unchanged (1.4/100,000/y), as was the incidence of non-meningitic infections in individuals < 60 y. There were no other important changes between the 2 studies, which confirm that invasive pneumococcal infections have the highest incidence rates in children < 2 y and in the elderly, that a wide variety of underlying conditions are seen in the patients and that the case fatality rate, 15% in the present study, is still high.
机译：在一项回顾性研究中，研究了1981-95年瑞典哥德堡地区的侵袭性肺炎球菌感染患者的发病率，临床表现，伴随疾病和病死率，当时肺炎球菌多糖疫苗可用但很少使用。从临床细菌学部门的记录以及相关部门基于计算机的出院记录中识别患者。发现了876例侵袭性肺炎球菌感染患者的个案记录，这些患者的病历经血液，脑脊液或其他无菌体液的培养证实。以前曾发表过来自同一地区，设计相同的研究报告，涵盖了1964-80年。从以前的研究到本研究，总发生率从5.3例/每年100,000 / y增加。这种增加是由于年龄大于或等于60岁的非脑膜炎感染患者的增加。脑膜炎的发生率几乎未发生变化（1.4 / 100,000 / y），<60岁的非脑膜炎感染的发生率也没有变化。两项研究之间没有其他重要变化，这证实侵入性肺炎球菌感染在2岁以下儿童和老年人中发病率最高，在患者中发现了多种潜在疾病，病死率本研究中的15％仍然很高。

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