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Combining traditional agents and biologics for the treatment of psoriasis.

机译:结合传统药物和生物制剂治疗牛皮癣。

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摘要

Psoriasis patients deserve long-term control of their disease with optimal safety. Traditional agents (methotrexate, cyclosporine, retinoids, and photochemotherapy [PUVS]), although providing excellent short-term control, may produce acute or chronic toxicities, thus limiting their usage. Dermatologists are well versed in combination and rotational therapies for psoriasis, using these and other agents. With the advent of biologic therapies (three currently approved, and others pending), the potential for safer long-term psoriasis control is being realized. A review of the literature, plus our personal experience in using combinations of traditional agents and biologics, is presented.
机译:银屑病患者应以最佳安全性长期控制其疾病。传统药物(甲氨蝶呤,环孢素,类维生素A和光化学疗法[PUVS])虽然提供出色的短期控制,但可能产生急性或慢性毒性,因此限制了它们的使用。皮肤科医生精通使用银屑病和其他药物的组合疗法和旋转疗法。随着生物疗法的出现(目前已批准三种,还有其他正在申请中),人们正在实现更安全的长期牛皮癣控制的潜力。介绍了文献综述,以及我们在使用传统药物和生物制剂组合方面的个人经验。

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