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Membrane technology for purification of enzymatically produced oligosaccharides: Molecular and operational features affecting performance

机译:膜技术纯化酶法生产的低聚糖:影响性能的分子和操作特征

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摘要

The immediate challenge in the fractionation and purification of biofunctional oligosaccharides, for example enzymatically manufactured prebiotics, is the coupling of chemical engineering knowledge on mass transport and membrane separation to the particular requirements and opportunities provided by carbohydrate-based products. This review provides an overview of the currently available knowledge and correlations between the particular properties of saccharides, e.g. their structural and physico-chemical characteristics, and membrane separation principles considering the potential influence of the operational modes and variables on the separation efficiency. The hitherto used membrane-based techniques, mainly ultra- and nanofiltration, and the conditions (membrane type, temperature, feed concentration, pressure) during separation and purification of different types of oligosaccharides are discussed. Lastly, the applicability of a number of novel separation techniques, vibrating membrane module, electrofiltra-tion, and backflushing are presented in relation to high-performance separation of oligosaccharides.
机译:分馏和纯化生物功能性低聚糖(例如酶法制备的益生元)的直接挑战是将基于质量传输和膜分离的化学工程知识与基于碳水化合物的产品提供的特定要求和机会结合起来。该综述概述了当前可获得的知识以及糖的特定性质之间的相关性,例如糖。它们的结构和物理化学特性,以及膜分离原理,其中考虑了操作模式和变量对分离效率的潜在影响。讨论了迄今为止使用的基于膜的技术,主要是超滤和纳滤,以及在分离和纯化不同类型的低聚糖过程中的条件(膜类型,温度,进料浓度,压力)。最后,与低聚糖的高效分离有关,提出了许多新型分离技术的适用性,如振动膜组件,电过滤和反吹。

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