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首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Autologous fat augmentation for voice and swallow improvement after cordectomy.
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Autologous fat augmentation for voice and swallow improvement after cordectomy.

机译:自体脂肪增加以改善脐带切除术后的声音和吞咽能力。

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Surgery for the treatment of early-stage glottic carcinoma still remains a valid option. In most patients, newly formed neocord tissue preserves glottic functions, but in some patients an important glottic gap leading to glottic insufficiency may occur. In our study, 11 patients who had serious glottic insufficiency after endoscopic laser and laryngofissure cordectomy were treated with autologous fat injection (AFI) into the neocord tissue for voice and swallowing rehabilitation. One patient did not attend the first control visit and was excluded from the study. The remaining 10 patients were evaluated in the preoperative and postoperative periods for phonatory functions and efficacy of AFI by videolaryngostroboscopy and computerized acoustic analysis. Phonatory functions showed statistically significant improvement in the shimmer, noise-to-harmonic ratio, maximum phonation time and fundamental frequency. Perceptual ratings (GRBAS scale) also showed statistically significant improvement in all 5 parameters. Despite improvement in glottic closure, the mucosal wave deteriorated. Due to recurrence of symptoms of glottic insufficiency, AFI was repeated in 2 patients at the third and fifth months, respectively. One year later, the AFI resulted in successful rehabilitation of swallowing in all patients. The probability of resorption of autologous fat and the deterioration of the mucosal wave after AFI remain a problem, but re-injection can be done easily. As AFI is an easy, safe and cheap method, we concluded that it is a promising alternative procedure for managing voice problems after laser or laryngofissure cordectomy defects.
机译:早期声门癌的手术治疗仍然是有效的选择。在大多数患者中,新形成的新脐带组织保留了声门功能,但在某些患者中,可能会发生导致声门功能不全的重要声门间隙。在我们的研究中,对11例在内窥镜激光和喉裂索切除术后出现严重声门功能不全的患者进行了自体脂肪注射(AFI)治疗,将其注入新绳组织中以进行语音和吞咽康复。一名患者未参加首次对照访视,被排除在研究之外。其余10例患者在术前和术后通过视频喉镜检查和计算机声学分析评估了AFI的语音功能和疗效。语音功能在闪烁,噪声与谐波比率,最大发声时间和基频上显示出统计学上的显着改善。感知等级(GRBAS量表)在所有5个参数上也显示出统计学上的显着改善。尽管声门闭合性有所改善,但粘膜波仍恶化。由于声门功能不全症状的复发,分别在第三个月和第五个月对2例患者进行了AFI重复检查。一年后,AFI导致所有患者的吞咽成功康复。自体脂肪吸收的可能性和AFI后粘膜波的恶化仍然是一个问题,但是再注射可以很容易地完成。由于AFI是一种简便,安全且便宜的方法,因此我们得出结论,它是一种有希望的替代方法,可用于处理激光或喉咙闭锁性脐带切除术后出现的声音问题。

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