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首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Combined medical and surgical therapy improves olfaction in patients with nasal polyposis
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Combined medical and surgical therapy improves olfaction in patients with nasal polyposis

机译：内科和外科手术相结合的疗法可改善鼻息肉病患者的嗅觉

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摘要

Objective: The aim of the present study was to evaluate the outcomes of combined oral steroid, nasal steroid and surgical therapy in patients with impaired olfaction due to nasal polyposis. Patients and Methods: This prospective observational study was undertaken in the otolaryngology department of a university hospital. During the study, 19 nasal polyposis patients were evaluated three times, i.e. before oral steroid therapy, before surgery (after steroid therapy) and after surgery, with smell identification tests, acoustic rhinometry, subjective smell score, endoscopic grading and a visual analog scale for nasal obstruction. Results: All subjective and objective measures were significantly improved after medical and surgical therapy (p < 0.01). The median smell identification score improved from 2 (interquartile range 0-4) to 5 (interquartile range 4-7) after combined therapy. Smell identification scores were found to be modestly correlated with all other examination findings. Conclusion: Combined therapy seems efficient in improving smell identification scores of nasal polyposis patients.
机译：目的：本研究的目的是评估口服类固醇，鼻类固醇和手术疗法联合治疗鼻息肉所致嗅觉受损的患者的疗效。患者与方法：这项前瞻性观察研究在大学医院的耳鼻咽喉科进行。在研究过程中，对19名鼻息肉病患者进行了3次评估，即在口服类固醇治疗之前，手术之前（类固醇治疗之后）和手术之后进行了3次评估，包括气味识别测试，声学鼻音测定法，主观气味评分，内窥镜分级和视觉模拟评分鼻塞。结果：药物和手术治疗后所有主观和客观指标均得到明显改善（p <0.01）。联合治疗后，气味识别中位数从2（四分位范围0-4）提高到5（四分位范围4-7）。发现气味识别分数与所有其他检查结果适度相关。结论：联合治疗似乎可以有效提高鼻息肉病患者的气味识别分数。

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