A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration

Hara Satoshi; Kawano Mitsuhiro; Mizushima Ichiro; Yamada Kazunori; Fujita Kentaro; Harada Kenichi; Matsumura Masami; Yamagishi Masakazu; Sato Yasuharu; Yamaguchi Yutaka; Nakanuma Yasuni; Nagata Michio

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A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration

机译：尽管没有血清IgG4升高和IgG4阳性浆细胞浸润，但仍紧密模仿IgG4相关疾病的疾病

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We describe a 74-year-old Japanese man with systemic fibroinflammatory conditions closely resembling those of immunoglobulin G4-related disease (IgG4-RD). Radiology and histology showed characteristics of IgG4-related tubulointerstitial nephritis, despite normal serum IgG4 value and scanty IgG4-positive plasma cell infiltration in each organ. This case suggests that a condition closely mimicking IgG4-RD may develop without IgG4-positive plasma cells and those exceptional cases should also be taken into account in the differential diagnosis of IgG4-RD.

机译：我们描述了一个74岁的日本男子，全身免疫性纤维炎的状况与免疫球蛋白G4相关疾病（IgG4-RD）极为相似。放射学和组织学检查显示，尽管每个器官中的血清IgG4值正常且IgG4阳性的浆细胞浸润很少，但IgG4相关的肾小管间质性肾炎的特征。这种情况表明，在没有IgG4阳性浆细胞的情况下，可能会出现非常类似于IgG4-RD的疾病，在IgG4-RD的鉴别诊断中也应考虑到那些特殊情况。

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来源
《Modern rheumatology》 |2016年第5期|共6页
作者
Hara Satoshi; Kawano Mitsuhiro; Mizushima Ichiro; Yamada Kazunori; Fujita Kentaro; Harada Kenichi; Matsumura Masami; Yamagishi Masakazu; Sato Yasuharu; Yamaguchi Yutaka; Nakanuma Yasuni; Nagata Michio;
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正文语种 eng
中图分类免疫性疾病;
关键词
IgG4-related disease; IgG4; Tubulointerstitial nephritis;

机译：IgG4相关疾病;IgG4;肾小管间质性肾炎;

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1. A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration [J] . Hara Satoshi, Kawano Mitsuhiro, Mizushima Ichiro, Modern rheumatology . 2016,第5期

机译：尽管没有血清IgG4升高和IgG4阳性浆细胞浸润，但仍紧密模仿IgG4相关疾病的疾病
2. Diagnostic sensitivity of cutoff values of IgG4-positive plasma cell number and IgG4-positive/CD138-positive cell ratio in typical multiple lesions of patients with IgG4-related disease [J] . Mizushima Ichiro, Yamada Kazunori, Harada Kenichi, Modern rheumatology . 2018,第2期

机译：IgG4阳性血浆细胞数和IgG4阳性/ CD138阳性细胞比率诊断敏感性典型多病变患者IgG4相关疾病患者的典型病变
3. A case of IgG4-positive plasma cell-rich tubulointerstitial nephritis in a kidney allograft mimicking IgG4-related kidney disease [J] . Nishikawa Kouhei, Takeda Asami, Masui Satoru, Nephrology. . 2014,第Suppla3期

机译：模仿IgG4相关肾脏疾病的同种异体肾移植中IgG4阳性浆细胞丰富的肾小管间质性肾炎1例
4. MTT Reduction by Flavonoids in the Absence of Cells: Influence of Medium Type and Serum [C] . Terence P.N. Talorete, Mohamed Bouaziz, Sami Sayadi, Annual Meeting of the Japanese Association for Animal Cell Technology . 2009

机译：在没有细胞的情况下，黄酮类化合物的MTT减少：中等类型和血清的影响
5. Development of plasma cleaning and plasma enhanced close space sublimation hardware for improving CdS/CdTe solar cells. [D] . Swanson, Drew. 2012

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6. 18F-fluoro-deoxyglucose positron emission tomography/computed tomography scan findings in Rosai-Dorfman disease with IgG4-positive plasma cell infiltration mimicking breast malignancy: a case report and literature review [O] . Liping Fu, Mei Liu, Zhigang Song, 2012

机译：Rosai-Dorfman病伴IgG4阳性浆细胞浸润模仿乳腺恶性肿瘤的18F-氟-脱氧葡萄糖正电子发射断层扫描/计算机断层扫描扫描结果：病例报告和文献复习
7. A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration [O] . Hara Satoshi, Kawano Mitsuhiro, Mizushima Ichiro, 2016

机译：尽管没有血清IgG4升高和IgG4阳性浆细胞浸润，但仍紧密模仿IgG4相关疾病的疾病

A condition closely mimicking IgG4-related disease despite the absence of serum IgG4 elevation and IgG4-positive plasma cell infiltration

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