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Comparison of video-assisted thyroidectomy and traditional thyroidectomy for the treatment of papillary thyroid carcinoma.

机译:电视辅助甲状腺切除术与传统甲状腺切除术治疗甲状腺乳头状癌的比较。

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BACKGROUND: There is concern regarding the oncological effectiveness of minimally invasive video-assisted thyroidectomy (VAT) for thyroid carcinoma. This study compared the surgical results of VAT and traditional thyroidectomy in patients with small papillary thyroid carcinomas (PTC). METHODS: Of 44 patients with PTC offered the choice between VAT and traditional thyroidectomy, 21 underwent VAT and 23 underwent traditional thyroidectomy. Residual thyroid tissue and function were assessed postoperatively by measuring thyroid-stimulating hormone (TSH), T4, thyroglobulin, and anti-thyroglobulin antibody levels and with sonographic examination. RESULTS: Operative time, maximum tumor size, number of positive lymph nodes, and TSH and T4 levels 4 weeks postoperatively were similar in the two groups (all p > 0.05). Patients in the traditional thyroidectomy group had significantly higher postoperative serum thyroglobulin levels 4 weeks after surgery than did patients in the VAT group (5.4 versus 0.5 ng/ml, respectively; p = 0.007). Postoperative ultrasonography showed no residual thyroid tissue or evidence of recurrence in any of the patients. The median follow-up period was 60 months (range 31-77 month) for the VAT group and 53 months (range 31-80 months) for the traditional thyroidectomy group. Thyroglobulin levels of all patients in both groups decreased to <0.2 ng/ml at last follow-up. CONCLUSIONS: VAT is safe and effective for the treatment of small papillary thyroid carcinomas, and has similar oncological effectiveness to traditional thyroidectomy.
机译:背景:人们担心微创电视辅助甲状腺切除术(VAT)对甲状腺癌的肿瘤学有效性。本研究比较了小乳头状甲状腺癌(PTC)患者的增值税和传统甲状腺切除术的手术效果。方法:在44例PTC患者中,他们选择了VAT和传统甲状腺切除术,其中21例接受了VAT,23例接受了传统甲状腺切除术。术后通过测量甲状腺刺激激素(TSH),T4,甲状腺球蛋白和抗甲状腺球蛋白抗体水平并进行超声检查来评估甲状腺的残余组织和功能。结果:两组的手术时间,最大肿瘤大小,阳性淋巴结数目以及术后4周的TSH和T4水平相似(均p> 0.05)。传统甲状腺切除术组的患者术后4周的血清甲状腺球蛋白水平明显高于VAT组(分别为5.4和0.5 ng / ml; p = 0.007)。术后超声检查未发现任何残留甲状腺组织或复发迹象。增值税组的中位随访期为60个月(31-77个月),传统甲状腺切除术组为53个月(31-80个月)。在最后一次随访时,两组所有患者的甲状腺球蛋白水平均降至<0.2 ng / ml。结论:增值税可安全有效地治疗小型甲状腺乳头状癌,其肿瘤学疗效与传统甲状腺切除术相似。

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