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首页> 外文期刊>Surgical Endoscopy >Staged laparoscopic adjuvant intraperitoneal chemohyperthermia after complete resection for locally advanced colorectal or gastric cancer: a preliminary experience.
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Staged laparoscopic adjuvant intraperitoneal chemohyperthermia after complete resection for locally advanced colorectal or gastric cancer: a preliminary experience.

机译：局部切除的局部晚期大肠癌或胃癌术后分期腹腔镜辅助腹腔内化学高热：初步经验。

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摘要

BACKGROUND: Cytoreductive surgery followed by intraperitoneal chemohyperthermia (IPCH) is a promising treatment for patients with peritoneal carcinomatosis, a disease with dismal prognosis. METHODS: We describe our preliminary experience with staged adjuvant laparoscopic IPCH after complete resection in patients with locally or regionally advanced colorectal or gastric cancer. RESULTS: Twenty-one patients underwent resection for colorectal (N = 16) or gastric cancer (N = 5) followed by staged laparoscopic IPCH. No conversion to laparotomy was required. No major operative incident occurred. Mean duration of hospital stay was 12 days (range 9-23 days). No mortality occurred in the 30-day postoperative period. Four patients developed major complications (19%). One patient (5%) was reoperated. Mean follow-up period was 15.5 months (range 9-29 months). Three patients died, including two of cancer-related causes. No patient developed peritoneal carcinomatosis during the follow-up period. CONCLUSION: Staged laparoscopic adjuvant IPCH after open or laparoscopic resection in selected patients with colorectal or gastric cancer is feasible and reasonably safe. However, additional data are required to determine the effect on long-term survival.
机译：背景：先进行细胞减灭术，然后进行腹膜内化学性高热（IPCH），是治疗腹膜癌病（预后不良的疾病）的一种有前途的治疗方法。方法：我们描述了局部或区域晚期结直肠癌或胃癌患者完全切除后分期腹腔镜IPCH的初步经验。结果：21例患者接受了大肠切除术（N = 16）或胃癌（N = 5），随后进行了腹腔镜IPCH。无需转换为剖腹手术。没有发生重大手术事件。平均住院时间为12天（9-23天）。术后30天无死亡发生。四名患者出现严重并发症（19％）。再次手术（5％）。平均随访期为15.5个月（范围为9-29个月）。 3例患者死亡，其中2例与癌症相关。随访期间无患者发生腹膜癌变。结论：对于部分结直肠癌或胃癌患者，在开腹或腹腔镜切除后分期腹腔镜辅助IPCH是可行且合理的。但是，需要其他数据来确定对长期生存的影响。

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