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首页> 外文期刊>Surgical Endoscopy >Postoperative pain relief after laparoscopic cholecystectomy: a placebo-controlled double-blind randomized trial of preincisional infiltration and intraperitoneal instillation of levobupivacaine 0.25%.
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Postoperative pain relief after laparoscopic cholecystectomy: a placebo-controlled double-blind randomized trial of preincisional infiltration and intraperitoneal instillation of levobupivacaine 0.25%.

机译：腹腔镜胆囊切除术后疼痛缓解：安慰剂对照双盲试验，术前0.25％左旋布比卡因及腹膜内滴注左旋布比卡因。

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摘要

BACKGROUND: The aim of this study was to test the use of preincisional and intraperitoneal levobupivacaine (L-B) 0.25% in laparoscopic cholecystectomies for postoperative analgesia. METHODS: A total of 108 patients under general anesthesia were randomly assigned to receive preincisional local infiltration of 20 ml solution and intraperitoneal instillation of another 20 ml solution. Group A received for local infiltration and intraperitoneal instillation normal saline (NS). Group B received for local infiltration L-B 0.25% and for intraperitoneal instillation NS. Group C received for local infiltration NS and for intraperitoneal instillation L-B 0.25%. Group D received both for local infiltration and intraperitoneal instillation L-B 0.25%. Abdominal and right shoulder pain were recorded for 24 h postoperatively. RESULTS: The pain scores were lower in group D than in the other groups during rest, cough, and movement (p < 0.05). Rescue analgesic treatment was significantly lower in patients of group D (35%) as compared with that of group A (84%) (p < 0.05). The incidence of right shoulder pain was significantly lower in groups C (22%) and D (18%) than in any of the other groups (p < 0.05). CONCLUSIONS: The combination of preincisional local infiltration and intraperitoneal instillation of L-B 0.25% shows an advantage for postoperative analgesia after laparoscopic cholecystectomy.
机译：背景：这项研究的目的是测试腹腔镜胆囊切除术中0.25％的切口前和腹膜内左旋布比卡因（L-B）的使用率。方法：总共108名接受全身麻醉的患者被随机分配接受术前局部浸润20 ml溶液和腹腔内滴注另一20 ml溶液的方法。 A组接受局部浸润和腹膜内滴注生理盐水（NS）。 B组接受0.25％的局部浸润L-B和腹膜内滴注NS。 C组接受局部浸润NS和腹膜内滴注L​​-B 0.25％。 D组接受局部浸润和腹膜内滴注0.25％L-B。术后24小时记录腹部和右肩疼痛。结果：在休息，咳嗽和运动期间，D组的疼痛评分低于其他组（p <0.05）。 D组的急诊镇痛治疗（35％）明显低于A组（84％）（p <0.05）。 C组（22％）和D组（18％）的右肩痛发生率显着低于其他任何组（p <0.05）。结论：术前局部浸润和腹膜内滴注L​​-B 0.25％的结合显示了腹腔镜胆囊切除术后的镇痛效果。

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