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Cytology of the salivary glands

机译:唾液腺细胞学

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Common usage of fine-needle aspirate (FNA) for salivary gland lesions is the preoperative determination of whether a lesion is neoplastic, its lineage, and if neoplastic, whether it is low grade/benign, or high grade. Immunohistochemical stains can be performed on cell blocks to determine lineage and help refine diagnosis, although their performance is not always equivalent to that seen in surgical specimens. Several characteristic translocations have been described in various entities in these categories, and these can be evaluated using fluorescence in situ hybridization. In the future, high-throughput next-generation sequencing panels may further refine cytologic diagnosis in salivary tumors.
机译:唾液腺病变的细针抽吸术(FNA)的常用用法是术前确定病变是否为赘生性,其谱系以及是否为赘生性,是低度/良性还是高度。免疫组织化学染色可以在细胞块上进行,以确定谱系并帮助完善诊断,尽管它们的表现并不总是与手术标本中的表现相同。在这些类别的各个实体中已描述了几种特征性易位,可以使用荧光原位杂交对其进行评估。将来,高通量的下一代测序专家组可能会进一步完善唾液肿瘤的细胞学诊断。

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