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Cirrhosis Regression and Subclassification.

机译:肝硬化退化和亚分类。

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The end point of liver fibrosis in almost all chronic liver diseases is cirrhosis. Progression to cirrhosis is accompanied by vascular remodeling and regeneration with important functional and hemodynamic consequences that include development of portal hypertension and eventually decompensation and death. Fibrosis can regress following successful treatment of the underlying disease. However, most common fibrosis scoring systems are not equipped for assessing this aspect. Nodule size, septal width and fibrosis area seem to correlate with disease severity and progression in cirrhosis. Classification systems based on nodule size, septal width, and fibrosis area need to be further validated.
机译:在几乎所有慢性肝病中,肝纤维化的终点是肝硬化。肝硬化的进展伴随着血管重塑和再生,具有重要的功能和血液动力学后果,包括门脉高压的发展以及最终代偿失调和死亡。成功治疗基础疾病后,纤维化可能会消退。但是,大多数常见的纤维化评分系统均未配备用于评估此方面的内容。结节大小,间隔宽度和纤维化面积似乎与肝硬化的疾病严重程度和进展相关。基于结节大小,间隔宽度和纤维化面积的分类系统需要进一步验证。

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