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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Spectrotemporal mapping of high-resolution ECGs in experimental myocardial infarction: comparison with time-domain analysis and epicardial electrograms.
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Spectrotemporal mapping of high-resolution ECGs in experimental myocardial infarction: comparison with time-domain analysis and epicardial electrograms.

机译：高分辨率心电图在实验性心肌梗死中的光谱时间图：与时域分析和心电图比较。

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The study was undertaken to evaluate the relationship of signal-averaged ECG (SA-ECG) readings in the frequency domain (STM) and epicardial electrograms (EE) recorded before and after acute myocardial infarction (AMI) in pigs and to compare the changes with findings in time-domain analysis (TDA). In 20 pigs the left anterior descending artery (LAD) was ligated. Prior to ligation, a SA-ECG was recorded (method of Simson) and bipolar electrodes were used to register EE in the areas supplied by the LAD and the circumflex artery (CIRC). Five minutes after LAD ligation, all measurements were repeated. Time-domain parameters were QRS duration (QRS D) and the duration of the signal below 30 microV (LAS 30). Beginning at a point of 20 ms before the QRS end, the frequency spectra (0-200 Hz) of 25 segments of 80-ms duration at the QRS end were analyzed. The volumes below the 25 curves were analyzed separately for 0-50 Hz, 51-100 Hz, 101-150 Hz, and 151-200 Hz. After AMI, five pigs died within 7 minutes. In 15 pigs, QRS D as well as LAS 30 lengthened significantly (P<0.05; P<0.001). Spectrotemporal mapping (STM) showed a significant decrease of the frequencies above 50 Hz (51-200 Hz) in the entire group and in the animals with late potentials (P<0.05). EE of the LAD area were significantly prolonged (P<0.01); this did not correlate with the changes in STM parameters. In pigs acute myocardial infarction causes a shift towards lower frequencies in the STM which most likely reflects the slowed depolarisation in the ischemic area.
机译：该研究旨在评估猪在急性心肌梗死（AMI）前后记录的频域（STM）和心外膜电图（EE）的平均信号心电图（SA-ECG）读数之间的关系，并比较这些变化与时域分析（TDA）的发现。在20只猪中，结扎左前降支动脉（LAD）。结扎之前，记录SA-ECG（Simson方法），并使用双极电极在LAD和回旋动脉（CIRC）提供的区域中记录EE。 LAD结扎后五分钟，重复所有测量。时域参数是QRS持续时间（QRS D）和低于30 microV的信号持续时间（LAS 30）。从QRS末端之前20 ms的点开始，分析QRS末端持续时间为80 ms的25个片段的频谱（0-200 Hz）。分别分析了25条曲线下方的音量，分别针对0-50 Hz，51-100 Hz，101-150 Hz和151-200 Hz。 AMI后7分钟内有5头猪死亡。在15头猪中，QRS D和LAS 30显着延长（P <0.05; P <0.001）。光谱时间图谱（STM）显示整个组和具有晚期电位的动物中高于50 Hz（51-200 Hz）的频率均显着降低（P <0.05）。 LAD区的EE明显延长（P <0.01）;这与STM参数的变化无关。在猪中，急性心肌梗死导致STM频率降低，这很可能反映了缺血区域去极化的减缓。

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