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首页> 外文期刊>PACE: Pacing and clinical electrophysiology >Relation of magnetocardiographic arrhythmia risk parameters to delayed ventricular conduction in postinfarction ventricular tachycardia.
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Relation of magnetocardiographic arrhythmia risk parameters to delayed ventricular conduction in postinfarction ventricular tachycardia.

机译：心肌梗死后室性心动过速的心律失常危险参数与室传导延迟的关系。

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摘要

Time-domain late field and intra-QRS fragmentation parameters in magnetocardiography (MCG) identify patients prone to VT after myocardial infarction. This study investigated if they are related to slow ventricular conduction and affected by arrhythmia surgery. Twenty-two patients with old myocardial infarction undergoing map-guided subendocardial resection to treat sustained VT were included. Bipolar electrograms were recorded during operation using an epicardial jacket and endocardial balloon electrode array. The time from the QRS onset to the end of local ventricular excitation in each electrogram was measured during sinus rhythm. Multi-channel MCG was recorded before and after operation and filtered QRS duration (QRSd), root mean square amplitude of the magnetic field strength during the last 40 ms of the QRS complex (RMS40), duration of the low amplitude signal < 300 fT (LAS300), fragmentation index M (M), and fragmentation score S (S) were determined. All patients had one or two VT foci localized and resected. MCG parameters correlated with time to the latest end of ventricular excitation; r = 0.45 for QRSd (P = 0.035), r = 0.64 for M (P = 0.001), and r = 0.73 for S (P < 0.001). The correlations were even better in patients with anterior infarction (e.g., r = 0.87 for QRSd, P < 0.001; r = 0.91 for M, P < 0.001). The operation reduced the abnormalities in MCG parameters and 20 of the 21 patients tested postoperatively became noninducible. MCG parameters indicating postinfarction arrhythmia propensity are related to delayed ventricular conduction. Abolition of the arrhythmia substrate reverses the abnormality of these parameters.
机译：心电图（MCG）中的时域晚场和QRS内碎裂参数可识别出心肌梗死后容易发生VT的患者。这项研究调查了它们是否与缓慢的心室传导有关，并受到心律不齐手术的影响。包括22例接受地图引导的心内膜下切除术治疗持续性室速的老年心肌梗死患者。使用心外膜外套和心内膜球囊电极阵列在手术期间记录双极电描记图。在窦性心律期间，测量每个电描记图中从QRS发作到局部心室兴奋结束的时间。记录手术前后的多通道MCG并过滤QRS持续时间（QRSd），QRS复合波的最后40 ms期间磁场强度的均方根振幅（RMS40），低振幅信号的持续时间<300 fT（确定了LAS300），碎片指数M（M）和碎片分数S（S）。所有患者均定位并切除了1或2个VT灶。 MCG参数与心室兴奋的最新结束时间相关; QRSd的r = 0.45（P = 0.035），M的r = 0.64（P = 0.001），S的r = 0.73（P <0.001）。前梗死患者的相关性甚至更好（例如QRSd的r = 0.87，P <0.001; M的r = 0.91，P <0.001）。手术减少了MCG参数的异常，术后21例患者中有20例无法诱发。指示梗死后心律失常倾向的MCG参数与心室传导延迟有关。取消心律不齐底物可逆转这些参数的异常。

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