Efficient Synthesis of Biologically Interesting Dehydro-alpha-Lapachone and alpha-Lapachone

Yong Rok Lee; Won Kyong Lee

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Efficient Synthesis of Biologically Interesting Dehydro-alpha-Lapachone and alpha-Lapachone

机译：高效合成生物有趣的脱氢-α-Lapachone和α-Lapachone

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摘要

An efficient synthesis of biologically active dehydro-alpha-lapachone and alpha-lapachone has been carried out starting from 2-hydroxy-1,4-naphtho-quinone by a tandem Knoevenagel-electrocyclic reaction.

机译：通过串联的Knoevenagel-电环反应，从2-羟基-1,4-萘醌开始有效地合成了生物活性的脱氢-α-拉帕酮和α-拉帕酮。

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来源
《Synthetic Communications》 |2004年第24期|共7页
作者
Yong Rok Lee; Won Kyong Lee;
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原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
Dehydro-alpha-lapachone; alpha-Lapachone; 2-Hydroxy-1; 4-naphthoquinone; Knoevenagel-electrocyclic reaction;

机译：脱氢-α-拉帕酮;α-拉帕酮;2-羟基-1;4-萘醌;Knoevenagel-电环反应;

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1. Efficient Synthesis of Biologically Interesting Dehydro-alpha-Lapachone and alpha-Lapachone [J] . Yong Rok Lee, Won Kyong Lee Synthetic Communications . 2004,第24期

机译：高效合成生物有趣的脱氢-α-Lapachone和α-Lapachone
2. New potential inhibitors of DNA topoisomerase. Part II: Design and synthesis of alpha-lapachone derivatives under microwave irradiation. [J] . Wei P, Zhang X, Tu S, Bioorganic and Medicinal Chemistry Letters . 2009,第3期

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Efficient Synthesis of Biologically Interesting Dehydro-alpha-Lapachone and alpha-Lapachone

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